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Sirtex Medical
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300 Unicorn Park Drive, Woburn MA 01801
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SIR-Spheres Y-90 resin microspheres is the first therapeutic radiopharmaceutical approved by the NMPA based on clinical trial data, for the treatment of patients with colorectal cancer liver metastases.


Lead Product(s): Yttrium Radioisotopes

Therapeutic Area: Oncology Product Name: SIR-Spheres Y-90

Highest Development Status: ApprovedProduct Type: Large molecule

Partner/Sponsor/Collaborator: Grand Pharmaceutical Group Limited

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 09, 2022

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Through this agreement, Sirtex gains an option to non-exclusively co-promote the Company's lead product candidate, TAVO™ (tavokinogene telseplasmid) in anti-PD-1 checkpoint refractory metastatic melanoma in the U.S.


Lead Product(s): Tavokinogene Telseplasmid,Pembrolizumab

Therapeutic Area: Oncology Product Name: Tavo

Highest Development Status: Phase IIProduct Type: Cell and Gene therapy

Recipient: OncoSec Immunotherapies

Deal Size: $30.0 million Upfront Cash: Undisclosed

Deal Type: Agreement January 19, 2021

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Sirtex will support and assist OncoSec with pre-marketing activities for TAVO™ and its visceral lesion applicator (VLA) in exchange for low single-digit royalties on those products.


Lead Product(s): Tavokinogene Telseplasmid,Pembrolizumab

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: Phase IIProduct Type: Cell and Gene therapy

Recipient: OncoSec Immunotherapies

Deal Size: $30.0 million Upfront Cash: $30.0 million

Deal Type: Partnership February 10, 2020

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