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Sareum
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United Kingdom
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Unit 2A, Langford Arch London Road, Pampisford Cambridge CB22 3FX
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+44 (0) 1223 497700

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SDC-1801 is a TYK2/JAK1 inhibitor being developed as a potential new therapeutic for a range of autoimmune diseases with an initial focus on psoriasis, an autoimmune condition affecting the skin.


Lead Product(s): SDC-1801

Therapeutic Area: Dermatology Product Name: SDC-1801

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 05, 2023

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SDC-1801 is a TYK2/JAK1 inhibitor being developed as a potential new therapeutic for a range of autoimmune diseases with an initial focus on psoriasis, an autoimmune condition affecting the skin.


Lead Product(s): SDC-1801

Therapeutic Area: Dermatology Product Name: SDC-1801

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable July 28, 2022

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The United States Patent and Trademark Office has now formally approved its patent application (US Patent Application no. 16/351,620), in respect of an invention associated with Sareum’s proprietary SDC-1802 TYK2/JAK1 Kinase Inhibitor Programme.


Lead Product(s): SDC-1802

Therapeutic Area: Immunology Product Name: SDC-1802

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 07, 2021

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Sareum’s received £174,000 in grant funding to investigate the therapeutic potential of SDC-1801, its selective, small molecule TYK2/JAK1 kinase inhibitor, in severe-phase Covid-19.


Lead Product(s): SDC-1801

Therapeutic Area: Infections and Infectious Diseases Product Name: SDC-1801

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: UKRI

Deal Size: $0.2 million Upfront Cash: Undisclosed

Deal Type: Funding December 03, 2020

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The patent will protect the SDC-1802 molecule and pharmaceutical preparations thereof. Subject to certain formalities being completed, the Company expects that the patent will be granted within three months.


Lead Product(s): SDC-1802

Therapeutic Area: Oncology Product Name: SDC-1802

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 08, 2020

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The authors concluded that an approach using selective TYK2/JAK1 inhibitors may lead to the development of a therapy for lupus that does not involve the harmful side effects of systemic immune system suppression and may benefit numerous lupus patients in need of new options.


Lead Product(s): SDC-1802

Therapeutic Area: Immunology Product Name: SDC-1802

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable July 24, 2020

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