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The collaboration aims to co-develop SGB-3908, an siRNA drug candidate targeting angiotensinogen for the treatment of hypertension. SGB-3908 is an IND-enabling stage siRNA drug developed based on SanegeneBio's proprietary LEAD™ (Ligand and Enhancer Assisted Delivery) platform.


Lead Product(s): SGB-3908

Therapeutic Area: Cardiology/Vascular Diseases Product Name: SGB-3908

Highest Development Status: IND EnablingProduct Type: Large molecule

Partner/Sponsor/Collaborator: Innovent Biologics

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration December 26, 2023

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Through the collaboration with Orbit, Sanegene is looking to develop a portfolio of advanced RNAi based Therapies. Orbit’s proprietary technology enables the screening of large libraries of peptides using a combination of DNA encoded libraries and bead-based presentation.


Lead Product(s): RNAi-based Therapy

Therapeutic Area: Genetic Disease Product Name: Undisclosed

Highest Development Status: DiscoveryProduct Type: Large molecule

Partner/Sponsor/Collaborator: Orbit Discovery

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration January 05, 2023

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