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Rome Therapeutics
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700 Main Street North, Cambridge, MA 02139, US
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ROME intends to use the funds to advance its drug candidate, RPT-2950, an inhibitor of LINE-1 reverse transcriptase (RT), through early clinical trials, including Phase 1 studies to evaluate safety and determine optimal dose, and further advancement of pipeline and platform.


Lead Product(s): RPT-2950

Therapeutic Area: Immunology Product Name: RPT-2950

Highest Development Status: IND EnablingProduct Type: Undisclosed

Partner/Sponsor/Collaborator: Johnson & Johnson

Deal Size: $149.0 million Upfront Cash: Undisclosed

Deal Type: Series B Financing September 12, 2023

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ROME’s mission is to harness the power of the repeatome – the roughly 60% of the human genome consisting of repetitive sequences of nucleic acids, known as repeats – to discover powerful new classes of medicines for cancer and autoimmune diseases.


Lead Product(s): Undisclosed

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: DiscoveryProduct Type: Undisclosed

Partner/Sponsor/Collaborator: Sanofi Ventures

Deal Size: $77.0 million Upfront Cash: Undisclosed

Deal Type: Series B Financing September 14, 2021

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The capital would help in clinical advancement of several promising drug targets identified by ROME and may boost launch of multiple discovery programs.


Lead Product(s): Undisclosed

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: DiscoveryProduct Type: Large molecule

Partner/Sponsor/Collaborator: ARCH Venture Partners

Deal Size: $50.0 million Upfront Cash: Undisclosed

Deal Type: Series A Financing April 27, 2020

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