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Rakuten Medical
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900 Concar Dr Suite 400 San Mateo, CA 9440
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858-925-5619
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Details:

Under the terms of the agreement, Hikma has an exclusive license to commercialize products in Rakuten Medical's pipeline using its photoimmunotherapy technology platform, Alluminox™, in all its MENA markets.


Lead Product(s): Cetuximab Sarotalocan Sodium

Therapeutic Area: Oncology Product Name: ASP-1929

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Hikma Pharmaceuticals

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement August 10, 2023

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Details:

The trial conducted for ASP-1929 photoimmunotherapy with fluorescence imaging, an antibody-dye conjugate binds to epidermal growth factor receptor, will assess efficacy and safety of surgical tumor resection in patients with operable primary or recurrent HNSCC or cuSCC.


Lead Product(s): ASP-1929 Photoimmunotherapy

Therapeutic Area: Oncology Product Name: ASP-1929

Highest Development Status: Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Shimadzu

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 15, 2022

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Details:

Rakuten Medical is conducting a global Phase 3 multi-center clinical trial with ASP-1929 IV Infusion (cetuximab sarotalocan sodium) in patients with recurrent head and neck squamous cell carcinoma.


Lead Product(s): Cetuximab Sarotalocan Sodium

Therapeutic Area: Oncology Product Name: Akalux

Highest Development Status: ApprovedProduct Type: Large molecule

Partner/Sponsor/Collaborator: Momentum Capital Markets

Deal Size: $166.0 million Upfront Cash: Undisclosed

Deal Type: Series D Financing July 28, 2021

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Details:

The data concluded that RM-1929 photoimmunotherapy showed a manageable safety profile in rHNSCC and showed tumor response in the heavily pre-treated patient population was clinically meaningful and warranted further investigation.


Lead Product(s): Cetuximab-conjugated IRDye 700DX

Therapeutic Area: Oncology Product Name: RM-1929

Highest Development Status: Phase I/ Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable July 08, 2021

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Details:

The trial will enroll three cohorts of patients within distinct populations. Primary endpoints of this study include safety, tolerability, and tumor response of the ASP-1929 photoimmunotherapy in combination with anti-PD1 therapy.


Lead Product(s): Cetuximab-conjugated IRDye700DX,Pembrolizumab

Therapeutic Area: Oncology Product Name: ASP-1929

Highest Development Status: Phase I/ Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 23, 2020

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Details:

IlluminoxTM technology platform developed ASP-1929 which binds to epidermal growth factor receptors (EGFR), a cancer antigen expressed in multiple types of solid tumors, including head and neck cancer, esophageal cancer, lung cancer, colon cancer, and pancreatic cancer.


Lead Product(s): Cetuximab-conjugated IRDye700DX

Therapeutic Area: Oncology Product Name: ASP-1929

Highest Development Status: Phase IIIProduct Type: Large molecule

Recipient: Medlight SA

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Acquisition August 19, 2020

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Details:

Under this agreement, Rakuten Medical may use cetuximab to produce ASP-1929 for clinical trials and commercial sales.


Lead Product(s): Cetuximab-conjugated IRDye700DX

Therapeutic Area: Oncology Product Name: ASP-1929

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Merck Group

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement July 07, 2020

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Details:

Under the signed MOU, NCC and Rakuten Medical will pursue multiple avenues to advance Illuminox-based cancer therapies. NCC will designate a lead principal who will act as an Illuminox Advisor.


Lead Product(s): ASP-1929

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: The National Cancer Center Japan

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration May 29, 2020

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