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QBiotics Group
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165 Moggill Rd, Taringa 4068 Queensland
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+61 7 3870 8933
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The study will evaluate the safety, optimal dose and tumour response of the tigilanol tiglate and pembrolizumab combination in patients with late-stage unresectable melanoma, who have been previously exposed to immune checkpoint inhibitors.


Lead Product(s): Tigilanol Tiglate,Pembrolizumab

Therapeutic Area: Oncology Product Name: EBC-46

Highest Development Status: Phase I/ Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 02, 2021

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The Phase I/II open label 'QBC46-H06' study is a dose escalation and expansion study with the primary objective of determining the maximum tolerated dose or maximum feasible dose of tigilanol tiglate, in combination with Keytruda® (pembrolizumab) therapy.


Lead Product(s): Tigilanol Tiglate,Pembrolizumab

Therapeutic Area: Oncology Product Name: EBC-46

Highest Development Status: Phase I/ Phase IIProduct Type: Small molecule

Recipient: Merck & Co

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration August 13, 2020

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