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Pulmocide
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United Kingdom
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44 Southampton Buildings London WC2A 1AP
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+44 203 763 9484
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PC945 (opelconazole), is a potent novel azole therapy specifically designed for inhaled use to maximize the amount of drug in the lung while providing minimal systemic exposure.


Lead Product(s): Opelconazole

Therapeutic Area: Infections and Infectious Diseases Product Name: PC945

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 15, 2024

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PC945 (opelconazole), is a potent novel azole therapy specifically designed for inhaled use to maximize the amount of drug in the lung while providing minimal systemic exposure.


Lead Product(s): Opelconazole

Therapeutic Area: Infections and Infectious Diseases Product Name: PC945

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 16, 2023

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Pulmocide’s opelconazole is a potent novel azole therapy specifically designed for inhaled use to maximize the amount of drug in the lung while providing minimal systemic exposure.


Lead Product(s): Opelconazole

Therapeutic Area: Infections and Infectious Diseases Product Name: PC945

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Pictet Alternative Advisors

Deal Size: $147.5 million Upfront Cash: Undisclosed

Deal Type: Series C Financing December 06, 2022

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The CF Foundation’s funding will support Phase 2 study of opelconazole. The objective of the study is to assess the safety and tolerability and patient’s ability to complete the course of treatment when used to prevent invasive pulmonary fungal infections in lung transplant.


Lead Product(s): Opelconazole

Therapeutic Area: Infections and Infectious Diseases Product Name: PC945

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Cystic Fibrosis Foundation

Deal Size: $3.5 million Upfront Cash: Undisclosed

Deal Type: Funding December 06, 2021

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Pulmocide’s lead product is opelconazole (PC945), a novel antifungal therapy specifically designed for inhaled use to maximize the amount of drug in the lung and spare systemic exposure.


Lead Product(s): Opelconazole

Therapeutic Area: Infections and Infectious Diseases Product Name: PC945

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 15, 2021

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Proceeds from the financing will primarily be used to advance the Company’s lead asset PC945 through a global Phase III registration program in patients with invasive pulmonary aspergillosis (IPA) who have failed prior therapy.


Lead Product(s): Opelconazole

Therapeutic Area: Infections and Infectious Diseases Product Name: PC945

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Jeito Capital

Deal Size: $92.0 million Upfront Cash: Undisclosed

Deal Type: Series C Financing May 27, 2021

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