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Details:
In this licensing agreement, PNI will provide lipid nanoparticle solutions for scale-up and manufacture of up to 15 Replicate srRNA therapeutics, including RBI-1000. The terms include aggregated milestone fees, royalties, and sublicensing income sharing.
Lead Product(s): RBI-1000
Therapeutic Area: Oncology Product Name: RBI-1000
Highest Development Status: PreclinicalProduct Type: Large molecule
Partner/Sponsor/Collaborator: Replicate Bioscience
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Licensing Agreement July 26, 2022
Details:
PNI will use the investment to advance a best-in-class COVID-19 mRNA vaccine candidate to clinical trials.
Lead Product(s): COVID-19 mRNA vaccine
Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed
Highest Development Status: UndisclosedProduct Type: Vaccine
Partner/Sponsor/Collaborator: Government of Canada
Deal Size: $18.2 million Upfront Cash: Undisclosed
Deal Type: Funding October 23, 2020
Details:
The collaboration aims at executing NanoAssemblr platform license and supply agreement, and successful production of multiple batches of Sirnaomics STP705 and STP707, for ongoing IND enabling safety and toxicity studies, as well as several clinical studies.
Lead Product(s): Cotsiranib
Therapeutic Area: Oncology Product Name: STP705
Highest Development Status: Phase IIProduct Type: Large molecule
Partner/Sponsor/Collaborator: Sirnaomics
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Partnership June 20, 2020
Details:
Under this collaboration, PNI will be responsible for development of the mRNA-LNP vaccine and CanSinoBIO will be responsible for pre-clinical testing, human clinical trials, regulatory approval and commercialization.
Lead Product(s): COVID-19 mRNA-LNP vaccine
Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed
Highest Development Status: UndisclosedProduct Type: Vaccine
Partner/Sponsor/Collaborator: CanSino Biologics
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Collaboration May 21, 2020
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