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Osivax
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Country
France
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Address
OSIVAX​​ ​99, rue de Gerland 69007 LYON
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Telephone
+33 4 37 65 55 03
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OVX836 is Osivax’ broad-spectrum influenza A vaccine candidate, in combination with quadrivalent influenza vaccines is being evaluated for the treatment of Influenza.


Lead Product(s): OVX836,Inactivated quadrivalent influenza vaccine

Therapeutic Area: Infections and Infectious Diseases Product Name: OVX836

Highest Development Status: Phase IIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 26, 2024

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OVX033 is a first-in-class coronavirus vaccine candidate that targets the nucleocapsid (N), a highly conserved internal antigen. Unlike surface antigens such as Spike (S), N is much less likely to mutate, providing a broader and more universal immune response.


Lead Product(s): OVX033

Therapeutic Area: Infections and Infectious Diseases Product Name: OVX033

Highest Development Status: Phase IProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 15, 2024

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The funding will support preclinical studies evaluating the breadth of protection and immune response induced by the company’s lead, broad-spectrum influenza vaccine candidate, OVX836 against pandemic influenza strains.


Lead Product(s): OVX836

Therapeutic Area: Infections and Infectious Diseases Product Name: OVX836

Highest Development Status: PreclinicalProduct Type: Vaccine

Partner/Sponsor/Collaborator: National Institute of Allergy and Infectious Diseases

Deal Size: $1.5 million Upfront Cash: Undisclosed

Deal Type: Funding December 05, 2023

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OVX836, a first-in-class broad-spectrum influenza vaccine candidate that targets the nucleoprotein (NP), a highly conserved internal antigen, is being evaluated in combination with Quadrivalent Influenza Vaccines (QIVs).


Lead Product(s): OVX836,Influenza Vaccine

Therapeutic Area: Infections and Infectious Diseases Product Name: OVX836

Highest Development Status: Phase IIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 15, 2023

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The funding will support additional research and development of its lead, broad-spectrum influenza vaccine candidate, OVX836 that targets the nucleoprotein (NP), a highly conserved internal antigen.


Lead Product(s): OVX836

Therapeutic Area: Infections and Infectious Diseases Product Name: OVX836

Highest Development Status: Phase IIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Bill & Melinda Gates Foundation

Deal Size: $1.0 million Upfront Cash: Undisclosed

Deal Type: Funding March 28, 2023

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OVX836 targets the nucleoprotein (NP), a highly conserved internal antigen. Unlike surface antigens, NP is much less likely to mutate, providing a broader and more universal immune response.


Lead Product(s): OVX836

Therapeutic Area: Infections and Infectious Diseases Product Name: OVX836

Highest Development Status: Phase IIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 21, 2022

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OVX836, targets the nucleoprotein (NP), a highly conserved internal antigen. Unlike surface antigens, NP is much less likely to mutate, providing a broader and more universal immune response.


Lead Product(s): OVX836,Quadrivalent Seasonal Influenza Subunit Vaccine

Therapeutic Area: Infections and Infectious Diseases Product Name: OVX836

Highest Development Status: Phase IIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 01, 2022

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Osivax will apply the funds to prepare OVX836 for a Phase 2b field efficacy clinical trial to assess its efficacy against a broad range of circulating strains. OVX836 targets the nucleoprotein (NP), a highly conserved internal antigen.


Lead Product(s): OVX836,Quadrivalent Seasonal Influenza Subunit Vaccine

Therapeutic Area: Infections and Infectious Diseases Product Name: OVX836

Highest Development Status: Phase IIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Bpifrance

Deal Size: $10.4 million Upfront Cash: Undisclosed

Deal Type: Funding June 23, 2022

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OVX836 is Osivax’ T-cell based influenza candidate developed using the company’s proprietary oligoDOM® nanoparticle technology platform and designed to produce immune responses against the nucleoprotein (NP), a highly conserved internal antigen across flu strains.


Lead Product(s): OVX836,Quadrivalent Seasonal Influenza Subunit Vaccine

Therapeutic Area: Infections and Infectious Diseases Product Name: OVX836

Highest Development Status: Phase IIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 25, 2022

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Under the collaboration, NIAID will provide its self-assembling ferritin nanoparticles that serve as scaffolding to display multiple copies of HA protein, expressed on the surface of influenza viruses, to Osivax for in vivo preclinical studies in combination with OVX836.


Lead Product(s): OVX836,Quadrivalent Seasonal Influenza Subunit Vaccine

Therapeutic Area: Infections and Infectious Diseases Product Name: OVX836

Highest Development Status: Phase IIProduct Type: Vaccine

Partner/Sponsor/Collaborator: National Institute of Allergy and Infectious Diseases

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration May 17, 2022

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