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Oragenics
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Country
U.S.A
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4902 Eisenhower Blvd. Suite 125 Tampa, FL 33634
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813-286-7900
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Details:

PRV-002 (ONP-002) is a first-in-class neurosteroid, which is being evaluated in phase 1 clinical trials for the treatment of mild traumatic brain injury.


Lead Product(s): ONP-002

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: PRV-002

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 05, 2024

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The Company intends to use the net proceeds from the offering to fund the continued development of ONP-002, a fully synthetic, non-naturally occurring neurosteroid, for the treatment of moderate to severe concussions.


Lead Product(s): ONP-002

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: ONP-002

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: ThinkEquity

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Public Offering March 01, 2024

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The company intends to use the net proceeds from the offering to fund the continued development of ONP-002, a unique neurosteroid drug compound intended to treat mild traumatic brain injuries also known as concussions.


Lead Product(s): ONP-002

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: ONP-002

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: ThinkEquity

Deal Size: $2.1 million Upfront Cash: Undisclosed

Deal Type: Public Offering February 27, 2024

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Details:

PRV-002 (ONP-002) is a first-in-class neurosteroid, which is being evaluated in phase 1 clinical trials for the treatment of mild traumatic brain injury.


Lead Product(s): ONP-002

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: PRV-002

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 05, 2024

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Details:

Through the acquisition, Oragenics gain Odyssey’s assets including drug candidates, ONP-002 for treating mild traumatic brain injury, and for treating Niemann Pick Disease Type C, as well as Odyssey’s proprietary powder formulation and its nasal delivery device.


Lead Product(s): ONP-002

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: ONP-002

Highest Development Status: Phase IProduct Type: Small molecule

Recipient: Odyssey Health

Deal Size: $1.0 million Upfront Cash: Undisclosed

Deal Type: Acquisition January 02, 2024

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Through the agreement, Oragenics acquire Odyssey’s assets including drug candidates, ONP-002 for treating mild traumatic brain injury, and for treating Niemann Pick Disease Type C, as well as Odyssey’s proprietary powder formulation and its nasal delivery device.


Lead Product(s): ONP-002

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: ONP-002

Highest Development Status: PreclinicalProduct Type: Small molecule

Recipient: Odyssey Health

Deal Size: $1.0 million Upfront Cash: Undisclosed

Deal Type: Acquisition October 05, 2023

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The funding will be used to develop a variant-agnostic protein antigen for use in its lead product, NT-CoV2-1, an intranasal vaccine candidate to prevent COVID-19 and variants of the SARS-CoV-2 virus.


Lead Product(s): NT-CoV2-1

Therapeutic Area: Infections and Infectious Diseases Product Name: NT-CoV2-1

Highest Development Status: IND EnablingProduct Type: Vaccine

Partner/Sponsor/Collaborator: CQDM

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Funding June 05, 2023

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Details:

Lantibiotics platform is focused on the development of new antibiotics effective against certain pathogens including vancomycin-resistant Enterococci (VRE) and methicillinresistant Staphylococcus aureus (MRSA).


Lead Product(s): Undisclosed

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 14, 2023

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Details:

Under the exclusive licensing agreement, Oragenics will pursue the development of its lead intranasal COVID-19 vaccine candidate, NT-CoV2-1 (SmT1v3) with Inspirevax’s novel BDX301 intranasal mucosal adjuvant.


Lead Product(s): SmT1v3,BDX301

Therapeutic Area: Infections and Infectious Diseases Product Name: NT-CoV2-1

Highest Development Status: PreclinicalProduct Type: Vaccine

Recipient: Inspirevax

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement March 01, 2023

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Details:

Its lead product is NT-CoV2-1, an intranasal vaccine candidate to prevent COVID-19 and variants of the SARS-CoV-2 virus. Its lantibiotics program features a novel class of antibiotics against bacteria that have developed resistance to commercial antibiotics.


Lead Product(s): NT-CoV2-1

Therapeutic Area: Infections and Infectious Diseases Product Name: NT-CoV2-1

Highest Development Status: PreclinicalProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 22, 2022

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