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Ochre Bio
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United Kingdom
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Bioescalator, Oxford, GB
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The partnership is focused on the discovery and development of novel, first-in-class regenerative treatments for chronic liver diseases (CLDs), such as late-stage metabolic dysfunction-associated steatohepatitis (MASH) cirrhosis.


Lead Product(s): RNA-based Therapy

Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: Undisclosed

Highest Development Status: DiscoveryProduct Type: Large molecule

Partner/Sponsor/Collaborator: Boehringer Ingelheim GmbH

Deal Size: $1,035.0 million Upfront Cash: $35.0 million

Deal Type: Partnership April 22, 2024

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Proceeds will support the development of first candidates for IND-enabling studies, as well as expand discovery and RNA chemistry capabilities to address a wider set of serious liver-related diseases.


Lead Product(s): siRNA Therapy

Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Large molecule

Partner/Sponsor/Collaborator: Khosla Ventures

Deal Size: $30.0 million Upfront Cash: Undisclosed

Deal Type: Series A Financing October 10, 2022

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Funding will be used to develop RNA therapies for transplant and chronic liver diseases. Ochre Bio has built a deep phenotyping platform to identify novel liver targets, validated directly in discarded human livers kept alive on machines.


Lead Product(s): RNA Therapies

Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Large molecule

Partner/Sponsor/Collaborator: Khosla Ventures

Deal Size: $9.6 million Upfront Cash: Undisclosed

Deal Type: Financing June 16, 2021

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