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OCE-205 is a therapeutic peptide with a differentiated mechanism of action. It is being evaluated in preclinical studies for the treatment of Ascites due to all etiologies except cancer.


Lead Product(s): OCE-205

Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: OCE-205

Highest Development Status: PreclinicalProduct Type: Peptide

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 20, 2023

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OCE-205 is a mixed agonist-antagonist therapeutic peptide that has a mechanism of action designed to selectively target consequences of the systemic hemodynamic complications associated with decompensated liver cirrhosis, or ESLD.


Lead Product(s): OCE-205

Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: OCE-205

Highest Development Status: Phase IIProduct Type: Peptide

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 24, 2022

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OCE-205 is a peptide therapeutic with a differentiated mechanism of action (MOA) designed to selectively target serious hemodynamic complications that are the result of liver fibrosis and portal hypertension in ESLD.


Lead Product(s): OCE-205

Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: OCE-205

Highest Development Status: Phase IIProduct Type: Peptide

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 22, 2022

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Proceeds will be used for lead clinical candidate, OCE-205, a peptide therapeutic with a mechanism of action designed to selectively target complications of portal hypertension that is being explored first in HRS-AKI.


Lead Product(s): OCE-205

Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: OCE-205

Highest Development Status: Phase IProduct Type: Peptide

Partner/Sponsor/Collaborator: RA Capital Management

Deal Size: $36.0 million Upfront Cash: Undisclosed

Deal Type: Series A Financing March 23, 2022

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