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Novotech (Australia) Pty Limited Level 3, 235 Pyrmont Street Australia
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PAS-004 is is a small molecule allosteric inhibitor of MEK 1/2. It is being evaluated for the treatment of neurofibromatosis type 1 and other cancer indications.


Lead Product(s): PAS-004

Therapeutic Area: Oncology Product Name: PAS-004

Highest Development Status: Phase IProduct Type: Small molecule

Recipient: Pasithea Therapeutics

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 13, 2024

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VYD222 was engineered from adintrevimab (ADG20), which provided neutralizing protection against SARS-CoV-2 for all variants of concern until the emergence of the Omicron BA.2 strain and its sublineages.


Lead Product(s): VYD222

Therapeutic Area: Infections and Infectious Diseases Product Name: VYD222

Highest Development Status: Phase IProduct Type: Large molecule

Recipient: Invivyd

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 26, 2023

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OLP-1002 is an SCN9A antisense peptide nucleic acid (PNA) and selectively inhibits the expression of Nav1.7 sodium channel, and therefore expected to replicate much of the phenotype of people with SCN9A channelopathy.


Lead Product(s): OLP-1002

Therapeutic Area: Musculoskeletal Product Name: OLP-1002

Highest Development Status: Phase IIProduct Type: Large molecule

Recipient: OliPass

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable July 18, 2022

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In the study NP-120 (Ifenprodil), demonstrated 65% of patients had stable or improved forced vital capacity (“FVC”) over the 12-week treatment period with statistical significance when compared to an anticipated placebo effect of 40%.


Lead Product(s): Ifenprodil Tartrate

Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: NP-120

Highest Development Status: Phase IIProduct Type: Small molecule

Recipient: Algernon Pharmaceuticals

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable July 18, 2022

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SBI-100, a proprietary prodrug of tetrahydrocannabinol (“THC”), is a topical formulation under development to treat glaucoma. SBI-100 enables enhanced local delivery of the drug into the eye, reduced systemic side effects and the potential for neuroprotection.


Lead Product(s): Tetrahydrocannabinol

Therapeutic Area: Ophthalmology Product Name: SBI-100

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Skye Bioscience

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement March 03, 2022

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The first in human clinical trial is randomized, double-blind, vehicle controlled study to determine the safety, tolerability, PK and efficacy of twice daily application of topical BioLexa™ lotion, in adult and adolescent patients with mild to moderate AD.


Lead Product(s): Gentamicin Sulfate,Pentetic Acid

Therapeutic Area: Dermatology Product Name: BioLexa

Highest Development Status: Phase IProduct Type: Small molecule

Recipient: Hoth Therapeutics

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 22, 2021

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XW003, a potential candidate for the treatment of non-alcoholic steatohepatitis (NASH), has been approved by China NMPA for clinical trial.


Lead Product(s): XW003

Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: XW003

Highest Development Status: Phase IProduct Type: Peptide

Recipient: Sciwind

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 28, 2021

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The new clinical trial is designed to evaluate the use of GP1681 as a potential new medicine to treat the severe immune response to COVID-19.


Lead Product(s): GP1681

Therapeutic Area: Immunology Product Name: GP1681

Highest Development Status: Phase IProduct Type: Small molecule

Recipient: CytoAgents

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 13, 2020

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The company said it seeks to expand the use of Panaphix to cover COVID-19 treatment through this proposed clinical trial.


Lead Product(s): Panaphix

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: UndisclosedProduct Type: Undisclosed

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 06, 2020

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