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The proceeds will be used to advance both Novome’s clinical hyperoxaluria candidate, NOV001, through an ongoing Phase 2a clinical trial and multiple Genetically Engineered Microbial Medicines (GEMMs) candidates for the potential treatment of inflammatory bowel disease (IBD).


Lead Product(s): NB1000S,NB2000P

Therapeutic Area: Gastroenterology Product Name: NOV-001

Highest Development Status: Phase I/ Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Tencent

Deal Size: $43.5 million Upfront Cash: Undisclosed

Deal Type: Series B Financing September 13, 2022

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NOV-001 is an investigational combination product composed of NB1000S and NB2000P. Preclinical studies of NOV001 showed consistent and robust reduction in urine oxalate levels in multiple animal models of disease.


Lead Product(s): NB1000S,NB2000P

Therapeutic Area: Gastroenterology Product Name: NOV-001

Highest Development Status: Phase I/ Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 17, 2021

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Under the terms of the agreement, Novome will have responsibility for research activities up to initiation of IND-enabling preclinical studies for this multi-target collaboration.


Lead Product(s): Genetically Engineered Microbial Medicines

Therapeutic Area: Gastroenterology Product Name: Undisclosed

Highest Development Status: DiscoveryProduct Type: Large molecule

Partner/Sponsor/Collaborator: Genentech

Deal Size: $605.0 million Upfront Cash: $15.0 million

Deal Type: Collaboration November 10, 2021

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The financing will be used to advance the company’s lead hyperoxaluria program through Phase 1 clinical proof-of-concept work, as well as to expand its (GEMMs) platform.


Lead Product(s): Undisclosed

Therapeutic Area: Nephrology Product Name: Undisclosed

Highest Development Status: DiscoveryProduct Type: Large molecule

Partner/Sponsor/Collaborator: DCVC Bio

Deal Size: $33.0 million Upfront Cash: Undisclosed

Deal Type: Series A Financing January 07, 2020

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