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Northwest Biotherapeutics
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U.S.A
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4800 Montgomery Lane Suite 800 Bethesda, MD 20814
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240-497-9024
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DCVax-L is a fully personalized immune therapy made from a patient's own immune cells (dendritic cells) and antigens (biomarkers) from a sample of the patient's own tumor.


Lead Product(s): Dendritic Cell Immunotherapy

Therapeutic Area: Oncology Product Name: DCVax-L

Highest Development Status: Phase IIIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 22, 2023

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Details:

DCVax-L is a fully personalized immune therapy made from a patient's own immune cells (dendritic cells) and antigens (biomarkers) from a sample of the patient's own tumor.


Lead Product(s): Dendritic Cell Immunotherapy

Therapeutic Area: Oncology Product Name: DCVax-L

Highest Development Status: Phase IIIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 13, 2023

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Details:

DCVax-L is a fully personalized immune therapy made from a patient's own immune cells (dendritic cells) and antigens (biomarkers) from a sample of the patient's own tumor.


Lead Product(s): Dendritic Cell Immunotherapy

Therapeutic Area: Oncology Product Name: DCVax-L

Highest Development Status: Phase IIIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 29, 2023

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Details:

DCVax-L is a fully personalized immune therapy made from a patient's own immune cells (dendritic cells) and antigens (biomarkers) from a sample of the patient's own tumor.


Lead Product(s): Dendritic Cell Immunotherapy

Therapeutic Area: Oncology Product Name: DCVax-L

Highest Development Status: Phase IIIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 17, 2022

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Substantial percentage of patients who received DCVax-L (Dendritic Cell Immunotherapy) in the prior Phase I/II clinical trials have continued in a “long tail” of survival far beyond even the 3 year median survival.


Lead Product(s): Dendritic Cell Immunotherapy

Therapeutic Area: Oncology Product Name: DCVax-L

Highest Development Status: Phase IIIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 05, 2022

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The Company’s lead program is a 331-patient Phase III trial of DCVax®-L for newly diagnosed Glioblastoma multiforme (GBM).


Lead Product(s): DCVax-L

Therapeutic Area: Oncology Product Name: DCVax-L

Highest Development Status: Phase IIIProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 05, 2020

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Flaskworks has developed a breakthrough system to close and automate the manufacturing of cell therapy products such as DCVax®.


Lead Product(s): DCVax-L

Therapeutic Area: Oncology Product Name: DCVax-L

Highest Development Status: Phase IIIProduct Type: Cell and Gene therapy

Recipient: Flaskworks

Deal Size: $4.3 million Upfront Cash: $1.6 million

Deal Type: Acquisition September 01, 2020

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Remaining outstanding clinical trial data for the Company’s Phase 3 trial of DCVax®-L for Glioblastoma brain cancer as described in the Company’s last report on July 24, 2020 has now been completed by the specialty analytics firms.


Lead Product(s): DCVax-L

Therapeutic Area: Oncology Product Name: DCVax-L

Highest Development Status: Phase IIIProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 19, 2020

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Data collection from all of the clinical trial sites for the Company's Phase 3 trial of DCVax®-L for Glioblastoma brain cancer (the "Trial") has been completed and all of the sites have signed off on the locking of their data.


Lead Product(s): DCVax-L

Therapeutic Area: Oncology Product Name: DCVax-L

Highest Development Status: Phase IIIProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable July 24, 2020

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The Company reported that the final data collection process for the Phase 3 trial of DCVax®-L for Glioblastoma brain cancer has been progressing steadily despite ongoing difficulties due to coronavirus-related limitations on operations and restrictions at trial sites.


Lead Product(s): DCVax-L

Therapeutic Area: Oncology Product Name: DCVax-L

Highest Development Status: ApprovedProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 02, 2020

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