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Neuren Pharmaceuticals
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Australia
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Neuren Pharmaceuticals Limited Suite 201, 697 Burke Road Camberwell VIC 3124
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+61 (3) 9092 0480
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Under the agreement, Acadia will acquire ex-North American rights to the drug as well as global rights in Rett syndrome and Fragile X syndrome to Neuren’s development candidate NNZ-2591, an investigational synthetic analogue of cGP, for Rett syndrome and Fragile X syndrome.


Lead Product(s): Cyclo-Glycyl-proline Analog

Therapeutic Area: Genetic Disease Product Name: NNZ-2591

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Acadia Pharmaceuticals

Deal Size: $463.0 million Upfront Cash: $100.0 million

Deal Type: Licensing Agreement July 13, 2023

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Details:

NNZ-2591 has ideal attributes – a unique mechanism of action, consistent and compelling results in the model of each disorder, a clearly identified optimum dose and proprietary manufacturing with high purity and yield.


Lead Product(s): Pyrrolo(1,2-a)pyrazine-1,4-dione, hexahydro-8a-(2-propenyl)-, (8aR)-

Therapeutic Area: Genetic Disease Product Name: NNZ-2591

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 01, 2021

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