Polpharma European CDMO Partner & API Manufacturer since 1951 Polpharma European CDMO Partner & API Manufacturer since 1951

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NephroDI Therapeutics
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U.S.A
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Philadelphia, PA 19103
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+1 857-891-0017
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The agreement aims for the clinical development of NephroDI’s asset, NDI-5001, a novel kidney-targeted small molecule AMPK activator, as a potential therapy for X-linked congenital Nephrogenic Diabetes Insipidus (NDI).


Lead Product(s): NDI-5001

Therapeutic Area: Rare Diseases and Disorders Product Name: NDI-5001

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: McQuade Center for Strategic Research and Development

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement June 22, 2023

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NephroDI’s lead product, NDI-5033 is a unique adenosine monophosphate activated kinase (AMPK) activator that can stimulate water reabsorption without causing hypoglycemia, decreasing overall urine output.


Lead Product(s): NDI-5033

Therapeutic Area: Genetic Disease Product Name: NDI-5033

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Xontogeny, LLC

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Financing May 12, 2021

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