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The collaboration aims to develop an alternative delivery mechanism for patients who can benefit from ACA-11 (pritumumab), Nascent's lead monoclonal antibody cancer treatment asset, for the treatment of Brain Cancer.


Lead Product(s): Pritumumab

Therapeutic Area: Oncology Product Name: ACA-11

Highest Development Status: Phase IProduct Type: Large molecule

Recipient: HypoSpray Pharma

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration March 19, 2024

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Pritumumab is a natural human antibody that binds to Cell surface Vimentin (also referred to as ectodomain vimentin), a protein expressed on the surface of epithelial cancers.


Lead Product(s): Pritumumab

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 13, 2022

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PTB is a natural human antibody that works by binding to Cell surface Vimentin (also referred to as ectodomain vimentin, or EDV), a protein expressed on the surface of epithelial cancers.


Lead Product(s): Pritumumab

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 08, 2021

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Company has officially opened its Phase I trial to evaluate Pritumumab (PTB), the Company’s lead Monoclonal Antibody (Mab) therapeutic asset, as a treatment option for Brain Cancer, including Malignant Primary Brain Tumors and adult Brain Metastases.


Lead Product(s): Pritumumab

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Hoag Memorial Hospital Presbyterian

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 24, 2021

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Nascent Biotech appointed Dr. Navpaul Singh MD as Chief Medical Consultant in charge of research into Pritumumab’s use with viral infections, including COVID-19.


Lead Product(s): Pritumumab

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: UndisclosedProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 24, 2020

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Research Collaboration Agreement to initiate a vaccine program for the potential prevention of COVID-19 or other viral infections. This effort will augment Nascent’s current development plants to investigate the utility of Pritumumab for the treatment of COVID-19.


Lead Product(s): Recombinant Mycobacterium Bovis Bacillus Calmette-Guerin

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: UndisclosedProduct Type: Vaccine

Recipient: Manhattan BioSolutions

Deal Size: $0.2 million Upfront Cash: $0.1 million

Deal Type: Collaboration May 12, 2020

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Nascent has initiated tests to assess its monoclonal antibody Pritumumab (PTB) against the novel coronavirus. Also, finalizing the human brain cancer trial’s timeline with help of a CRO.


Lead Product(s): Pritumumab

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: UndisclosedProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 22, 2020

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Pritumumab, the lead asset of Nascent which targets cell surface vimentin, will be studied as a potential therapeutic agent against (Coronavirus) Covid-19.


Lead Product(s): Pritumumab

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: UndisclosedProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 03, 2020

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