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Ketamir-2 is a novel oral ketamine analog which could potentially deliver ultra-rapid antidepressant effects by inhibiting NMDA receptor. It is being evaluated for the treatment of major depressive disorder with suicidal ideation & treatment-resistant depression.


Lead Product(s): Ketamine Hydrochloride

Therapeutic Area: Psychiatry/Psychology Product Name: Ketamir-2

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Frontage Laboratories, Inc

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 02, 2024

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The collaboration aims to assist MIRA in the research and development of Ketamir-2 (ketamir analog), which aids individuals struggling with major depressive disorder with suicidal ideation.


Lead Product(s): Ketamine Analog

Therapeutic Area: Psychiatry/Psychology Product Name: Ketamir-2

Highest Development Status: PreclinicalProduct Type: Small molecule

Recipient: Pharmaseed

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration February 08, 2024

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Under the agreement, MIRA will have the exclusive right in the U.S., Canada, and Mexico to develop and commercialize Ketamir-2, a novel oral ketamine analog designed to revolutionize the landscape of depressive disorder treatments.


Lead Product(s): Ketamine Analog

Therapeutic Area: Psychiatry/Psychology Product Name: Ketamir-2

Highest Development Status: PreclinicalProduct Type: Small molecule

Recipient: Miralogx

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement November 20, 2023

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The collaboration aims to enhance MIRA's visibility within the investment community and spotlight the potential of its drug candidate, MIRA1a (synthetic tetrahydrocannabinol analog), in treating anxiety, cognitive decline, and neuropathic pain.


Lead Product(s): Synthetic Tetrahydrocannabinol Analog

Therapeutic Area: Psychiatry/Psychology Product Name: MIRA1a

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: MZ Group

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration September 05, 2023

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The company expects to use the net proceeds to advance its clinical development programs, including MIRA1a (synthetic tetrahydrocannabinol analog), being developed as the first prescription drug to target the CB1 and CB2 receptors for chronic pain and anxiety.


Lead Product(s): Tetrahydrocannabinol Analog,Cannabidiol

Therapeutic Area: Psychiatry/Psychology Product Name: MIRA1A

Highest Development Status: IND EnablingProduct Type: Small molecule

Partner/Sponsor/Collaborator: Kingswood Investments

Deal Size: $8.9 million Upfront Cash: Undisclosed

Deal Type: Public Offering August 07, 2023

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The company expects to use the net proceeds to advance its clinical development programs, including MIRA1a (synthetic tetrahydrocannabinol analog), being developed as the first prescription drug to target the CB1 and CB2 receptors for chronic pain and anxiety.


Lead Product(s): Synthetic Tetrahydrocannabinol Analog

Therapeutic Area: Psychiatry/Psychology Product Name: MIRA1a

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Kingswood Investments

Deal Size: $8.9 million Upfront Cash: Undisclosed

Deal Type: Public Offering August 02, 2023

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