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Two companies will start their collaboration with a focus on developing in vivo gene-editing therapies for liver-targeted diseases. This agreement strengthens Bayer’s new cell and gene therapy platform.


Lead Product(s): In Vivo Gene Therapy

Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: Undisclosed

Highest Development Status: Discovery PlatformProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Bayer AG

Deal Size: $1,040.0 million Upfront Cash: $40.0 million

Deal Type: Collaboration January 10, 2022

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The combination of Mammoth’s unique technology with Vertex’s unmatched experience in serious disease research and development will only accelerate programs with the goal of reaching patients with high unmet medical need.


Lead Product(s): In-vivo Gene-editing Therapies

Therapeutic Area: Genetic Disease Product Name: Undisclosed

Highest Development Status: UndisclosedProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Vertex Pharmaceuticals

Deal Size: $691.0 million Upfront Cash: $41.0 million

Deal Type: Collaboration October 26, 2021

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