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MaaT Pharma
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France
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317 Avenue Jean Jaurès 69007 Lyon
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MaaT013 is a full-ecosystem, off-the-shelf, standardized, pooled-donor, enema Microbiome Ecosystem TherapyTM for acute, hospital use. It is being evaluated in combination with Ipilimumab for the treatment of metastatic melanoma.


Lead Product(s): MaaT013,Ipilimumab,Nivolumab

Therapeutic Area: Oncology Product Name: MaaT013

Highest Development Status: Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 05, 2024

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MaaT033 is a an oral, donor-derived, standardized, high-richness, high-diversity microbiome ecosystem therapies, for ambulatory use, containing Butycore. It is being evaluated for the treatment of amyotrophic lateral sclerosis.


Lead Product(s): MaaT033

Therapeutic Area: Neurology Product Name: MaaT033

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 29, 2024

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The funding will be used forcompany's Phase 2b, evaluating MaaT033, an oral, donor-derived, standardized, high-richness, high-diversity microbiome ecosystem therapy, to improve overall survival for patients receiving second allogeneic stem cell transplantation (allo-HSCT2).


Lead Product(s): MaaT033

Therapeutic Area: Oncology Product Name: MaaT033

Highest Development Status: Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Bpifrance

Deal Size: $8.0 million Upfront Cash: Undisclosed

Deal Type: Funding November 30, 2023

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MaaT033 is an allo-HCT, oral, donor-derived, standardized, high-richness, high-diversity microbiome ecosystem therapies, which is investigated for the treatment of patients undergoing Hematopoietic Stem Cell transplantation.


Lead Product(s): MaaT033

Therapeutic Area: Immunology Product Name: MaaT033

Highest Development Status: Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 06, 2023

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MaaT013 contains butycore which aims to restore the symbiotic relationship between the patient’s functional gut microbiome and their immune system to correct the responsiveness and tolerance of immune functions and reduce steroid-resistant, gastrointestinal-predominant aGvHD.


Lead Product(s): MaaT013

Therapeutic Area: Immunology Product Name: MaaT013

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 27, 2023

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Details:

MaaT033 is an allo-HCT, oral, donor-derived, standardized, high-richness, high-diversity microbiome ecosystem therapies, which is investigated for the treatment of patients undergoing Hematopoietic Stem Cell transplantation.


Lead Product(s): MaaT033

Therapeutic Area: Immunology Product Name: MaaT033

Highest Development Status: Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 07, 2023

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Details:

MaaT013 contains butycore which aims to restore the symbiotic relationship between the patient’s functional gut microbiome and their immune system to correct the responsiveness and tolerance of immune functions and reduce steroid-resistant, gastrointestinal-predominant aGvHD.


Lead Product(s): MaaT013

Therapeutic Area: Immunology Product Name: MaaT013

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 24, 2023

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Details:

MaaT033 is an allo-HCT, oral, donor-derived, standardized, high-richness, high-diversity microbiome ecosystem therapies, for ambulatory use, containing Butycore , a group of bacterial species known to produce anti-inflammatory short-chain-fatty acid.


Lead Product(s): MaaT033

Therapeutic Area: Neurology Product Name: MaaT033

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 27, 2023

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Details:

MaaT013 contains butycore which aims to restore the symbiotic relationship between the patient’s functional gut microbiome and their immune system to correct the responsiveness and tolerance of immune functions and reduce steroid-resistant, gastrointestinal-predominant aGvHD.


Lead Product(s): MaaT013

Therapeutic Area: Immunology Product Name: MaaT013

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 03, 2023

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Details:

MaaT013 is a donor-derived, standardized, high-richness, high-diversity microbiome ecosystem therapy, containing ButycoreTM , a group of bacterial species known to produce anti-inflammatory short-chain-fatty acids.


Lead Product(s): MaaT013

Therapeutic Area: Immunology Product Name: MaaT013

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 10, 2022

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