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Lipella Pharmaceuticals
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U.S.A
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7800 Susquehanna St, Suite 505 Pittsburgh, PA 15208
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1-412-894-1853
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LP-410 is designed to target the underlying mechanisms of Oral Graft-Versus-Host Disease (GVHD), potentially providing a safe and effective treatment option for affected individuals.


Lead Product(s): LP-410

Therapeutic Area: Immunology Product Name: LP-410

Highest Development Status: IND EnablingProduct Type: Undisclosed

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 05, 2024

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LP-310 is a oral rinse formulation of LP-10, which is act as Increased local concentration in oral cavity while minimalizing systemic toxicity, which is investigated for the treatment of Graft-versus-Host Disease.


Lead Product(s): Liposomal Tacrolimus

Therapeutic Area: Immunology Product Name: LP-310

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 10, 2023

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LP-310 is a oral rinse formulation of LP-10, which is act as Increased local concentration in oral cavity while minimalizing systemic toxicity, which is investigated for the treatment of oral Lichen Planus.


Lead Product(s): Liposomal Tacrolimus

Therapeutic Area: Immunology Product Name: LP-310

Highest Development Status: IND EnablingProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 20, 2023

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The collaboration aims to facilitate Chemistry, Manufacturing, and Control documentation for Lipella's drug candidate LP-10 (liposomal tacrolimus), aimed at treating hemorrhagic cystitis. LP-10 has been granted Orphan Drug Designation by the FDA.


Lead Product(s): Tacrolimus

Therapeutic Area: Urology Product Name: LP-10

Highest Development Status: Phase IIProduct Type: Small molecule

Recipient: Cook MyoSite

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration April 17, 2023

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Details:

LP-10 is a proprietary liposomal formulation of tacrolimus that is currently being evaluated as a treatment for moderate to severe hemorrhagic cystitis. The product candidate is currently in Phase 2a clinical trial.


Lead Product(s): Tacrolimus

Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Product Name: LP-10

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 11, 2023

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A multi-site, prospective, open-label, dose-escalation clinical trial assessing the safety and efficacy of LP-10 (liposomal tacrolimus) is now open for recruitment at several sites.


Lead Product(s): Tacrolimus

Therapeutic Area: Urology Product Name: LP-10

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 15, 2020

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