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Ixaka
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United Kingdom
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45 Pont Street London SW1X 0BD
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Details:

Through the acquisition, Alaya.bio intends to leverage its combined assets to significantly simplify the way CAR-T cell therapies are being developed, manufactured and administered.


Lead Product(s): CAR T-cell Therapy

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Alaya.bio

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Acquisition October 20, 2023

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TNP – composed of proprietary polymer capsule ‘OM-PBAE’ polymers (oligopeptide end-modified poly β-amino-ester polymers) directed to specific cells through targeting agents attached capsule (an aptamer-based targeting moiety) and celtic (Lentivirus Based CAR T-cell Therapy).


Lead Product(s): Lentivirus Based CAR T-cell Therapy

Therapeutic Area: Oncology Product Name: Celtic

Highest Development Status: PreclinicalProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 21, 2022

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The collaboration will evaluate the safety and efficacy of antigen-specific SOMAmer® reagents previously identified and screened by SomaLogic as potential candidates for combination with Ixaka’s anti-CD3 aptamers.


Lead Product(s): AntigenxCD3 Bispecific Aptamers

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Cell and Gene therapy

Recipient: SomaLogic

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration June 29, 2021

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The new business will continue to develop Ixaka’s proprietary technologies – concentrated multi-cell therapies and targeted nanoparticle therapeutics. REX-001, Ixaka’s lead MCT product, is an autologous cell-based product in clinical development for the treatment of CLTI.


Lead Product(s): Rexmyelocel-T

Therapeutic Area: Cardiology/Vascular Diseases Product Name: REX-001

Highest Development Status: Phase IIIProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Undisclosed

Deal Size: $55.9 million Upfront Cash: Undisclosed

Deal Type: Financing January 18, 2021

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