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1601 Trapelo Rd. Suite 178 Waltham, MA 02451
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Pemgarda (pemivibart) formerly known as VYD222 is a broadly neutralizing, half-life extended monoclonal antibody (mAb) candidate, which is indicated for pre-exposure prophylaxis (PrEP) of COVID-19.


Lead Product(s): Pemivibart

Therapeutic Area: Infections and Infectious Diseases Product Name: Pemgarda

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 22, 2024

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Details:

Pemgarda (pemivibart) formerly known as VYD222 is a broadly neutralizing, half-life extended monoclonal antibody (mAb) candidate, which is indicated for pre-exposure prophylaxis (PrEP) of COVID-19.


Lead Product(s): Pemivibart

Therapeutic Area: Infections and Infectious Diseases Product Name: Pemgarda

Highest Development Status: ApprovedProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 22, 2024

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VYD222 is a broadly neutralizing, half-life extended monoclonal antibody (mAb) candidate, which is under phase 3 clinical development for the prevention of symptomatic COVID-19 in vulnerable populations, such as immunocompromised people.


Lead Product(s): VYD222

Therapeutic Area: Infections and Infectious Diseases Product Name: VYD222

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 03, 2024

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Details:

VYD222 is a broadly neutralizing, half-life extended monoclonal antibody (mAb) candidate, which is under phase 3 clinical development for the prevention of symptomatic COVID-19 in vulnerable populations, such as immunocompromised people.


Lead Product(s): VYD222

Therapeutic Area: Infections and Infectious Diseases Product Name: VYD222

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 18, 2023

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Details:

VYD222 is a broadly neutralizing, half-life extended monoclonal antibody (mAb) candidate in development for the prevention of symptomatic COVID-19 in vulnerable populations, such as immunocompromised people.


Lead Product(s): VYD222

Therapeutic Area: Infections and Infectious Diseases Product Name: VYD222

Highest Development Status: Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 11, 2023

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VYD222, half-life extended monoclonal antibody, was engineered from adintrevimab (ADG20), which provided neutralizing protection against SARS-CoV-2 for all variants of concern until the emergence of the Omicron BA.2 strain and its sublineages.


Lead Product(s): VYD222

Therapeutic Area: Infections and Infectious Diseases Product Name: VYD222

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable July 17, 2023

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Details:

VYD222 was engineered from adintrevimab (ADG20), which provided neutralizing protection against SARS-CoV-2 for all variants of concern until the emergence of the Omicron BA.2 strain and its sublineages.


Lead Product(s): VYD222

Therapeutic Area: Infections and Infectious Diseases Product Name: VYD222

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Novotech

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 26, 2023

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Details:

VYD222 was engineered from adintrevimab (ADG20), which provided neutralizing protection against SARS-CoV-2 for all variants of concern until the emergence of the Omicron BA.2 strain and its sublineages.


Lead Product(s): VYD222

Therapeutic Area: Infections and Infectious Diseases Product Name: VYD222

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 22, 2023

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Details:

VYD222 was engineered from adintrevimab (ADG20), which provided neutralizing protection against SARS-CoV-2 for all variants of concern until the emergence of the Omicron BA.2 strain and its sublineages.


Lead Product(s): VYD222

Therapeutic Area: Infections and Infectious Diseases Product Name: VYD222

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 25, 2023

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Details:

VYD222 was engineered from adintrevimab (ADG20), which provided neutralizing protection against SARS-CoV-2 for all variants of concern until the emergence of the Omicron BA.2 strain and its sublineages.


Lead Product(s): VYD222

Therapeutic Area: Infections and Infectious Diseases Product Name: VYD222

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 30, 2023

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