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IMV’s lead candidate, DPX-Survivac (maveropepimut-S), delivers antigenic peptides from survivin, a well-recognized cancer antigen commonly overexpressed in advanced cancers.
Lead Product(s): Maveropepimut-S,Pembrolizumab,Cyclophosphamide
Therapeutic Area: Oncology Product Name: DPX-Survivac
Highest Development Status: Phase IIProduct Type: Vaccine
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable February 13, 2023
Details:
IMV’s lead candidate, DPX-Survivac (maveropepimut-S), delivers antigenic peptides from survivin, a well-recognized cancer antigen commonly overexpressed in advanced cancers.
Lead Product(s): Maveropepimut-S,Pembrolizumab
Therapeutic Area: Oncology Product Name: DPX-Survivac
Highest Development Status: Phase IIProduct Type: Vaccine
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable January 08, 2023
Details:
DPX-Survivac (maveropepimut-S) is a novel T cell immunotherapy that uses the DPX platform to elicit strong and sustained survivin-specific T cell responses against tumor cells.
Lead Product(s): Maveropepimut-S,Pembrolizumab,Cyclophosphamide
Therapeutic Area: Oncology Product Name: DPX-Survivac
Highest Development Status: Phase IIProduct Type: Vaccine
Partner/Sponsor/Collaborator: H.C. Wainwright & Co.
Deal Size: $9.0 million Upfront Cash: Undisclosed
Deal Type: Public Offering December 20, 2022
Details:
DPX-Survivac (maveropepimut-S) is a novel T cell immunotherapy that uses the DPX platform to elicit strong and sustained survivin-specific T cell responses against tumor cells.
Lead Product(s): Maveropepimut-S,Pembrolizumab,Cyclophosphamide
Therapeutic Area: Oncology Product Name: DPX-Survivac
Highest Development Status: Phase IIProduct Type: Vaccine
Partner/Sponsor/Collaborator: H.C. Wainwright & Co.
Deal Size: $9.0 million Upfront Cash: Undisclosed
Deal Type: Public Offering December 16, 2022
Details:
IMV’s lead candidate, DPX-Survivac (maveropepimut-S, MVP-S), delivers antigenic peptides from survivin, a well-recognized cancer antigen commonly overexpressed in advanced cancers.
Lead Product(s): Maveropepimut-S,Pembrolizumab
Therapeutic Area: Oncology Product Name: DPX-Survivac
Highest Development Status: Phase IIProduct Type: Vaccine
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable December 15, 2022
Details:
Maveropepimut-S (DPX-Survivac) Generating Cancer-Targeted Killer T Cells combines advantages of DPX platform and cancer antigen survivin, is lead candidate of IMV’s new class of immunotherapies that generates cancer-targeted T cells in vivo.
Lead Product(s): Maveropepimut-S,Cyclophosphamide
Therapeutic Area: Oncology Product Name: DPX-Survivac
Highest Development Status: Phase IIProduct Type: Vaccine
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable April 28, 2022
Details:
Combination of DPX-Survivac (maveropepimut-s) and pembrolizumab showed encouraging clinical activity in advanced, metastatic bladder cancer patients, particularly in patients who had received prior immune checkpoint inhibitor therapy.
Lead Product(s): Maveropepimut-S,Pembrolizumab,Cyclophosphamide
Therapeutic Area: Oncology Product Name: DPX-Survivac
Highest Development Status: Phase IIProduct Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable April 08, 2022
Details:
DPX-Survivac, a novel T cell immunotherapy that uses the DPX platform to elicit a coordinated anti-tumor immune response involving natural killer cells in both translational and preclinical studies.
Lead Product(s): Maveropepimut-S,Cyclophosphamide
Therapeutic Area: Oncology Product Name: DPX-Survivac
Highest Development Status: Phase IIProduct Type: Vaccine
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable March 09, 2022
Details:
The Company has successfully completed preclinical safety, GLP toxicology as well as immunogenicity and challenge studies confirming a favorable safety profile and potential for the long duration of antibody titers and protection against SARS-CoV-2.
Lead Product(s): DPX-COVID-19
Therapeutic Area: Infections and Infectious Diseases Product Name: DPX-COVID-19
Highest Development Status: PreclinicalProduct Type: Vaccine
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable December 28, 2020
Details:
Results from the ongoing study continue to demonstrate prolonged clinical benefits, alongside favorable tolerability, and translational data linking the observed clinical benefits with DPX-Survivac’s mechanism of action.
Lead Product(s): DPX-Survivac,Cyclophosphamide
Therapeutic Area: Oncology Product Name: DPX-Survivac
Highest Development Status: Phase IIProduct Type: Vaccine
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable December 03, 2020
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