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ImmunogenX
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Through the acquisition, First Wave will advance its lead product candidate IMGX003 (latiglutenase) for research & development and commercialization purposes. Currently, it is being evaluated in Phase II clinical trial studies for the treatment of Celiac disease.


Lead Product(s): Latiglutenase

Therapeutic Area: Gastroenterology Product Name: IMGX003

Highest Development Status: Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: First Wave BioPharma

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Merger March 14, 2024

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Through the acquisition, First Wave will advance its lead product candidate IMGX003 (latiglutenase) for research & development and commercialization purposes. Currently, it is being evaluated in Phase II clinical trial studies for the treatment of Celiac disease.


Lead Product(s): Latiglutenase

Therapeutic Area: Gastroenterology Product Name: IMGX003

Highest Development Status: Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: First Wave BioPharma

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Merger December 18, 2023

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The company is developing latiglutenase (IMGX003) for celiac disease therapy. ImmunogenX is also developing a diagnostic tool for celiac disease management as a minimally-invasive monitor of villus health to follow the state of recovery of a celiac patient.


Lead Product(s): Latiglutenase

Therapeutic Area: Gastroenterology Product Name: IMGX003

Highest Development Status: Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Mayo Clinic

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 12, 2022

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CeliacShield Trial is a double-blind, placebo controlled, gluten challenge trial of the efficacy, safety and tolerability of 6-weeks treatment of Latiglutenase (IMGX003) administration in patients with well-controlled celiac disease.


Lead Product(s): Latiglutenase

Therapeutic Area: Immunology Product Name: IMGX003

Highest Development Status: Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: National Institutes of Health

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 18, 2021

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The trial will test the safety and efficacy of the company’s lead therapeutic candidate, Latiglutenase (IMGX003).


Lead Product(s): Latiglutenase

Therapeutic Area: Gastroenterology Product Name: Undisclosed

Highest Development Status: Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 13, 2020

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