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IBC-Ab002 is a novel, fully human anti-PD-L1 monoclonal antibody designed to harness the peripheral immune system to rewire brain/immune communication and protect the brain from functional loss in the patients with alzheimer's disease.


Lead Product(s): IBC-Ab002

Therapeutic Area: Neurology Product Name: IBC-Ab002

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 17, 2023

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The grant will be used to support the first-in-human clinical study of IBC-Ab002, a proprietary anti-PD-L1 antibody developed and engineered with differentiating characteristics tailored for the treatment of Alzheimer’s disease.


Lead Product(s): IBC-Ab002

Therapeutic Area: Neurology Product Name: IBC-Ab002

Highest Development Status: IND EnablingProduct Type: Large molecule

Partner/Sponsor/Collaborator: NIA

Deal Size: $5.0 million Upfront Cash: Undisclosed

Deal Type: Funding August 27, 2021

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The grant will phase 1 clinical trial to examine safety and activity of its proprietary antibody, IBC-Ab002, targeted to enhance the immune system and induce brain repair processes in individuals with Alzheimer’s disease.


Lead Product(s): IBC-Ab002

Therapeutic Area: Neurology Product Name: IBC-Ab002

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Alzheimer’s Association

Deal Size: $1.0 million Upfront Cash: Undisclosed

Deal Type: Funding September 01, 2020

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