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Through the acquisition, the combined company will advance the development of first-in-class tRNA-based therapeutics to target genetic disease and cancer.


Lead Product(s): tRNA-based Therapeutic

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: Discovery PlatformProduct Type: Large molecule

Recipient: 4SR Biosciences

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Acquisition January 17, 2023

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hC Bio’s innovations in precision protein editing therapies target genetically-defined diseases including cancer. A single tRNA therapy has the potential to treat many diseases, regardless of the gene or location of the mutation.


Lead Product(s): Engineered tRNA-based Therapeutic

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: UndisclosedProduct Type: Large molecule

Partner/Sponsor/Collaborator: Taiho Ventures

Deal Size: $40.0 million Upfront Cash: Undisclosed

Deal Type: Series A Financing November 04, 2022

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hC Bio is simultaneously developing a second tRNA-based platform called SWTX (“Switch”) to target diseases caused by missense mutations. This technology is designed to correct for such mutations in proteins that cause disease.


Lead Product(s): tRNA-based Therapeutics

Therapeutic Area: Genetic Disease Product Name: Undisclosed

Highest Development Status: UndisclosedProduct Type: Large molecule

Partner/Sponsor/Collaborator: ARCH Venture Partners

Deal Size: $24.0 million Upfront Cash: Undisclosed

Deal Type: Series A Financing February 23, 2022

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