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Flexion Therapeutics
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Country
Country
U.S.A
Address
Address
10 Mall Road, Suite 301, Burlington, MA 01803
Telephone
Telephone
781.305.7777

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Details:

This acquisition is a major milestone to build a robust offering of novel, non-opioid treatments to improve patient care along the neural pain pathway while simultaneously providing a complementary commercial asset in ZILRETTA for the treatment of OA knee pain.


Lead Product(s): Triamcinolone Acetonide

Therapeutic Area: Neurology Product Name: Zilretta

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Pacira BioSciences

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Acquisition October 11, 2021

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Company to expand FX201 low dose and mid dose cohorts to include up to 20 additional patients in each treatment group. Clinical data from the first two cohorts indicate that FX201 appears to be generally safe and well-tolerated at the low and mid doses.


Lead Product(s): Humantakinogene hadenovec

Therapeutic Area: Musculoskeletal Product Name: FX201

Highest Development Status: Phase IProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 18, 2021

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Previously presented preclinical findings show FX301 provided greater sustained, post-operative analgesic effect with no significant impairment in motor function compared to liposomal bupivacaine and placebo.


Lead Product(s): Funapide

Therapeutic Area: Neurology Product Name: FX301

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 05, 2020

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Five patients treated in first cohort of Phase 1 clinical trial evaluating the safety and tolerability of FX201; Drug Monitoring Committee (DMC) supported the initiation of the next dosing cohort.


Lead Product(s): Humantakinogene hadenovec

Therapeutic Area: Musculoskeletal Product Name: FX201

Highest Development Status: Phase IProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 08, 2020

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New animal data show FX301 provided sustained, post-operative analgesic effect with no impairment in motor function compared to liposomal bupivacaine and placebo.


Lead Product(s): Funapide

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 27, 2020

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Details:

Under the terms of the agreement, Flexion will be solely responsible for the manufacture and supply of ZILRETTA to HK Tainuo for all clinical and commercial activities.


Lead Product(s): Omadacycline

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: HK Tainuo

Deal Size: $42.5 million Upfront Cash: $10.0 million

Deal Type: Licensing Agreement April 01, 2020

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