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Eikonoklastes Therapeutics
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981 HILL STREET,CINCINNATI
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The partnership will advance Eikonoklastes’ AAV-based gene therapy, ET-101, into clinical trials for the treatment of patients with amyotrophic lateral sclerosis (ALS).


Lead Product(s): ET-101

Therapeutic Area: Neurology Product Name: ET-101

Highest Development Status: PreclinicalProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Forge Biologics

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Partnership November 29, 2022

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The company’s 1st-in-class gene therapy ET-101 has been engineered to overexpress Caveolin-1, which organizes and regulates synaptic receptors essential for neuromuscular signaling and function.


Lead Product(s): ET-101

Therapeutic Area: Neurology Product Name: ET-101

Highest Development Status: PreclinicalProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 09, 2022

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Funding will support Investigational New Drug (IND) enabling studies for Eikonoklastes Therapeutics’ L-ICON3 immune conjugate platform.


Lead Product(s): L-ICON3

Therapeutic Area: Oncology Product Name: L-ICON3

Highest Development Status: PreclinicalProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: CincyTech

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Series A Financing June 28, 2021

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