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EdiGene
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Building 2, No. 22, Science Park Road, Zhongguancun Life Science Park, Changping District, Beijing
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EdiGene’s high-throughput genome-editing screening platform uses high-throughput screening and bioinformatics analysis to develop new biomarkers and potential targeted therapies.


Lead Product(s): Undisclosed

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: Discovery PlatformProduct Type: Undisclosed

Partner/Sponsor/Collaborator: Peking University Cancer Hospital

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration April 13, 2022

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The collaboration will leverage EdiGene’s expertise in high-throughput genome editing screening and Neukio’s strength in the development and manufacturing of induced pluripotent stem cell (iPSC) and natural killer cell (NK Cell).


Lead Product(s): iPSC-CAR-NK Cell Therapy

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: Discovery PlatformProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Neukio Biotherapeutics

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration February 09, 2022

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Partnering with leading engineered cell therapy developers is a key component of Arbor’s strategy to broaden the potential of CRISPR discovery engine beyond the wholly-owned in vivo genetic medicine approaches for the benefit of even more patients.


Lead Product(s): Ex-vivo Engineered Cell Therapy

Therapeutic Area: Genetic Disease Product Name: Undisclosed

Highest Development Status: Discovery PlatformProduct Type: Cell and Gene therapy

Recipient: Arbor Pharmaceuticals

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement February 08, 2022

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Under the agreement, both parties will develop hematopoietic stem cell regenerative therapies, ET-01, including the development of genetically-modified hematopoietic stem cell therapies and exploration of novel biomarkers to optimize quality control for stem cell production.


Lead Product(s): ET-01

Therapeutic Area: Genetic Disease Product Name: ET-01

Highest Development Status: Phase IProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Haihe Laboratory

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration January 24, 2022

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Under the partnership, EdiGene will work with the David Gamm Laboratory to evaluate the pharmacological property of LEAPER™ RNA employs short engineered ADAR-recruiting RNAs (arRNAs) base editing candidates targeting specific genetic diseases.


Lead Product(s): Short Engineered ADAR-recruiting RNAs

Therapeutic Area: Genetic Disease Product Name: arRNAs

Highest Development Status: DiscoveryProduct Type: Large molecule

Partner/Sponsor/Collaborator: University of Wisconsin–Madison

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration November 09, 2021

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ET-01 is an autologous, in vitro gene editing therapy product in the research and development stage. The clinical trial approved this time is a multi-center, open, single-arm clinical study.


Lead Product(s): ET-01

Therapeutic Area: Genetic Disease Product Name: ET-01

Highest Development Status: IND EnablingProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 18, 2021

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EdiGene has established four gene editing based platforms and is advancing its early stage programs into clinical development for patients with genetic diseases and cancer. Proceeds from the financing will be used to advance the company’s pipeline into clinics.


Lead Product(s): ET-01

Therapeutic Area: Genetic Disease Product Name: ET-01

Highest Development Status: PreclinicalProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: 3H Health Investment

Deal Size: $67.0 million Upfront Cash: Undisclosed

Deal Type: Series B Financing October 13, 2020

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