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Ducentis BioTherapeutics
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United Kingdom
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264 Banbury Road, Oxford, Oxfordshire, OX2 7DY
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DS-234 is a fusion protein that is a highly selective and potent agonist of CD200R, an immune-regulatory receptor thought to be an important immunological checkpoint, with a pivotal role in maintenance of immune tolerance.


Lead Product(s): DS-234

Therapeutic Area: Dermatology Product Name: DS-234

Highest Development Status: PreclinicalProduct Type: Large molecule

Partner/Sponsor/Collaborator: Arcutis Biotherapeutics

Deal Size: $400.0 million Upfront Cash: $16.0 million

Deal Type: Acquisition September 08, 2022

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DS-234 offers a potential best-in-class profile, as well as a highly complementary treatment option to roflumilast cream which is in late-stage development for atopic dermatitis.


Lead Product(s): DS-234

Therapeutic Area: Dermatology Product Name: DS-234

Highest Development Status: PreclinicalProduct Type: Large molecule

Partner/Sponsor/Collaborator: Arcutis Biotherapeutics

Deal Size: $30.0 million Upfront Cash: $16.0 million

Deal Type: Acquisition September 07, 2022

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