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Details:
CYTO-102 to be an off-the-shelf cell therapy that can directly kill cancer cells, broadly stimulate the body’s own endogenous immune system, and enhance tumor killing through generation of a highly effective immune response ultimately leading to improved patient outcomes.
Lead Product(s): CYTO-102,Atezolizumab
Therapeutic Area: Oncology Product Name: CYTO-102
Highest Development Status: Phase IProduct Type: Cell and Gene therapy
Partner/Sponsor/Collaborator: City of Hope
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable July 28, 2022
Details:
CYTO NK-201, an engineered, allogeneic, tumor-reactive natural killer (TRACK-NK) and FLT3, directly attack cancer cells and broadly stimulate both innate and adaptive arms of immune system through potent IL-15 secretion enabling potential for potent and specific tumor killing.
Lead Product(s): CYTO NK-201
Therapeutic Area: Oncology Product Name: CYTO NK-201
Highest Development Status: IND EnablingProduct Type: Cell and Gene therapy
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable March 08, 2022
Details:
The agreements include licenses to several patent applications related to methods to generate large numbers of fully functional natural killer (NK) cells derived from umbilical cord blood and compositions of chimeric receptors (CAR) for targeting NK cells to tumors.
Lead Product(s): CYTO NK-203
Therapeutic Area: Oncology Product Name: CYTO NK-203
Highest Development Status: IND EnablingProduct Type: Cell and Gene therapy
Partner/Sponsor/Collaborator: City of Hope
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Licensing Agreement April 08, 2021
Details:
Cytovia will conduct and finance all future development and will apply the EGFR Dual-targeting CAR to its iPSC CAR NK technology. CytoImmune will receive an upfront equity grant in Cytovia, future development milestones, and royalties.
Lead Product(s): CYT-101
Therapeutic Area: Oncology Product Name: CYT-101
Highest Development Status: IND EnablingProduct Type: Cell and Gene therapy
Partner/Sponsor/Collaborator: Cytovia Therapeutics
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Acquisition August 03, 2020