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Clover Biopharmaceuticals
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China
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B-A10 Room No.1, Mansion Chengdu Hi-tech Zone Hi-tech Incubation Park, Tianhe Incubator, Nan Yan Xian Tian Fu Avenue, 610041 Chengdu
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(028)85336966
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SCB-1019 is the company's bivalent RSV prefusion-stabilized F (PreF)-Trimer subunit vaccine candidate. It is being evaluated for the treatment of respiratory syncytial virus infections.


Lead Product(s): SCB-1019

Therapeutic Area: Infections and Infectious Diseases Product Name: SCB-1019

Highest Development Status: Phase IProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 08, 2024

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SCB-219M is an innovative TPO-RA mimetic bispecific Fc-fusion protein produced from CHO cells. It is under phase 1 clinical development for the treatment of cancer patients with chemotherapy-induced thrombocytopenia.


Lead Product(s): SCB-219M

Therapeutic Area: Hematology Product Name: SCB-219M

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 28, 2023

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SCB-1019 is a vaccine drug candidate, which is currently being evaluated for the treatment of patients with respiratory syncytial virus (RSV) infections.


Lead Product(s): SCB-1019

Therapeutic Area: Infections and Infectious Diseases Product Name: SCB-1019

Highest Development Status: Phase IProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 12, 2023

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AdimFlu-S (QIS) is a quadrivalent split inactivated vaccine that can be used for the prevention of influenza. It contains hemagglutinin from four influenza virus strains (two A and two B).


Lead Product(s): Quadrivalent Seasonal Influenza Vaccine

Therapeutic Area: Infections and Infectious Diseases Product Name: AdimFlu-S

Highest Development Status: ApprovedProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 11, 2023

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Under the partnership, Clover will leverage Kyuan Trade’s extensive sales and distribution network to complement in-house capabilities and maximize access to its quadrivalent seasonal influenza vaccine, AdimFlu-S (QIS), across China.


Lead Product(s): Influenza A virus vaccine

Therapeutic Area: Infections and Infectious Diseases Product Name: AdimFlu-S

Highest Development Status: ApprovedProduct Type: Vaccine

Partner/Sponsor/Collaborator: Keyuan Xinhai

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Partnership May 23, 2023

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Under the terms of the agreement, Clover gains commercial rights to AdimFlu-S (quadrivalent influenza vaccine) in mainland China, Bangladesh, Brazil and the Philippines. AdimFlu-S is a quadrivalent split inactivated vaccine intended for use in the prevention of influenza.


Lead Product(s): Quadrivalent Influenza Vaccine

Therapeutic Area: Infections and Infectious Diseases Product Name: AdimFlu-S

Highest Development Status: ApprovedProduct Type: Vaccine

Recipient: Adimmune

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement February 19, 2023

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SCB-2019 antigen, a stabilized trimeric form of the S-protein based on the original strain of the SARS-CoV-2 virus, and combined it with Dynavax’s CpG 1018 advanced adjuvant and aluminum hydroxide (alum). Clover is developing it as a universal booster for COVID-19.


Lead Product(s): CpG 1018,Aluminium Hydroxide

Therapeutic Area: Infections and Infectious Diseases Product Name: SCB-2019

Highest Development Status: ApprovedProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 14, 2023

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SCB-2019 antigen, a stabilized trimeric form of the S-protein based on the original strain of the SARS-CoV-2 virus, and combined it with Dynavax’s CpG 1018 advanced adjuvant and aluminum hydroxide (alum). Clover is developing it as a universal booster for COVID-19.


Lead Product(s): CpG 1018,Aluminium Hydroxide

Therapeutic Area: Infections and Infectious Diseases Product Name: SCB-2019

Highest Development Status: ApprovedProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 15, 2023

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SCB-2019 (CpG 1018), a stabilized trimeric form of S-protein based on original strain of SARS-CoV-2 virus, demonstrated that household contact was 84% less likely to get SARS-CoV-2 infection when infected household member had received.


Lead Product(s): SCB-2019

Therapeutic Area: Infections and Infectious Diseases Product Name: SCB-2019

Highest Development Status: Phase IIIProduct Type: Vaccine

Partner/Sponsor/Collaborator: International Vaccine Institute

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 30, 2022

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SCB-2019 (CpG 1018) antigen, a stabilized trimeric form of the S-protein is based on the original strain of the SARS-CoV-2 virus. Clover created its COVID-19 vaccine candidate by combining SCB-2019 with Dynavax’s CpG 1018 advanced adjuvant and alum.


Lead Product(s): CpG 1018,Aluminium Hydroxide

Therapeutic Area: Infections and Infectious Diseases Product Name: SCB-2019

Highest Development Status: Phase IIIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 19, 2022

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