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Cidara Therapeutics
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U.S.A
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6310 Nancy Ridge Drive, Suite 101 San Diego, CA 92121
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(858) 752-6170

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Through the divestment, Mundipharma received the rights for Rezzayo (rezafungin acetate), an echinocandin antifungal, approved for the treatment of invasive candidiasis in adults.


Lead Product(s): Rezafungin

Therapeutic Area: Infections and Infectious Diseases Product Name: Rezzayo

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Mundipharma

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Divestment April 24, 2024

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Cidara has regained exclusive global development and commercial rights for CD388, which is under development for preventing all strains of influenza A and B.


Lead Product(s): CD388

Therapeutic Area: Infections and Infectious Diseases Product Name: CD388

Highest Development Status: Phase IIProduct Type: Small molecule

Recipient: Johnson & Johnson

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Acquisition April 24, 2024

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The net gross proceeds will be utilized to finance the clinical advancement of CD388, currently undergoing mid-stage clinical trials with patients for treating influenza.


Lead Product(s): CD388

Therapeutic Area: Infections and Infectious Diseases Product Name: CD388

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: RA Capital Management

Deal Size: $240.0 million Upfront Cash: Undisclosed

Deal Type: Private Placement April 24, 2024

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The payment triggered under the agreement is following the European approval of Rezzayo (rezafungin acetate), a novel, once-weekly echinocandin antifungal approved for the treatment of invasive candidiasis in adults.


Lead Product(s): Rezafungin

Therapeutic Area: Infections and Infectious Diseases Product Name: Rezzayo

Highest Development Status: ApprovedProduct Type: Peptide

Partner/Sponsor/Collaborator: Mundipharma

Deal Size: $568.0 million Upfront Cash: $39.0 million

Deal Type: Partnership February 12, 2024

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Rezzayo (rezafungin acetate) is a novel once-weekly echinocandin antifungal approved by USFDA. It is now approved by MHRA for the treatment of invasive candidiasis in adults.


Lead Product(s): Rezafungin

Therapeutic Area: Infections and Infectious Diseases Product Name: Rezzayo

Highest Development Status: ApprovedProduct Type: Peptide

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 29, 2024

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Rezzayo (rezafungin) is an echinocandin antifungal that helps to inhibit the synthesis of 1,3-beta-D-glucan, an essential component of fungal cell walls. It recently got EU approval for the treatment of invasive candidiasis in adults.


Lead Product(s): Rezafungin

Therapeutic Area: Infections and Infectious Diseases Product Name: Rezzayo

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 22, 2023

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Rezzayo (rezafungin acetate) is a novel once-weekly echinocandin and 1,3-beta-glucan synthase inhibitor. It is approved for the treatment for Invasive Candidiasis in adults.


Lead Product(s): Rezafungin

Therapeutic Area: Infections and Infectious Diseases Product Name: Rezzayo

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 06, 2023

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Rezafungin is a novel once-weekly echinocandin being developed for both the treatment and prevention of serious fungal infections, such as invasive candidiasis and candidemia.


Lead Product(s): Rezafungin

Therapeutic Area: Infections and Infectious Diseases Product Name: Rezzayo

Highest Development Status: ApprovedProduct Type: Small molecule

Recipient: Mundipharma

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 13, 2023

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Under the agreement, Cidara is studying CD388, a second generation, anti-viral Fc conjugate (AVC), in Phase 1 and 2a clinical trials evaluating safety and pharmacokinetics as well as efficacy as pre-exposure prophylaxis against an influenza virus.


Lead Product(s): CD388

Therapeutic Area: Infections and Infectious Diseases Product Name: CD388

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Johnson & Johnson Innovative Medicine

Deal Size: $780.0 million Upfront Cash: $27.0 million

Deal Type: Licensing Agreement September 06, 2023

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Rezzayo (rezafungin) is a novel, once-weekly, next-generation echinocandin, an antifungal being developed for both the treatment and prevention of serious fungal infections, such as candidemia and invasive candidiasis.


Lead Product(s): Rezafungin

Therapeutic Area: Infections and Infectious Diseases Product Name: Rezzayo

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable July 31, 2023

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