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Ceapro
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Country
Canada
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Address
7824-51 Avenue NW Edmonton, Alberta T6E 6W2
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Telephone
780.421.4555

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The combined company will focus on the development of AEZS-130 (macimorelin), a ghrelin receptor agonist and a small molecule that stimulates the secretion of growth hormone from the pituitary gland.


Lead Product(s): Macimorelin

Therapeutic Area: Neurology Product Name: AEZS-130

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Aeterna Zentaris

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Merger December 14, 2023

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Avenanthramides provide relief from a host of skin conditions, such as eczema, allergic rash, chicken pox and insect bites. Ceapro is the only commercial manufacturer of commercially available avenanthramides extracted and purified from oats.


Lead Product(s): Undisclosed

Therapeutic Area: Immunology Product Name: Undisclosed

Highest Development Status: Phase I/ Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 13, 2023

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Avenanthramides (AVA) are di-phenolic compounds found only in oats and are of interest due to suggested bioactivities, including antioxidant and anti-inflammatory effects in vitro and in vivo.


Lead Product(s): Undisclosed

Therapeutic Area: Immunology Product Name: Undisclosed

Highest Development Status: Phase I/ Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 27, 2023

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Data demonstrated that PGX-processed yeast beta glucan (PGX-YBG) is respirable and able to safely and reliably reprogram macrophages in the lungs in pre-clinical mouse models.


Lead Product(s): PGX-processed Yeast Beta Glucan

Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: PGX-YBG

Highest Development Status: PreclinicalProduct Type: Large molecule

Partner/Sponsor/Collaborator: McMaster University

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 23, 2023

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Oat-based bioactives BG and AV exhibited potential to improve regenerative wound healing, reduce inflammation, promote angiogenesis, and reduce scar formation.


Lead Product(s): Oat Beta Glucan

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Angiogenesis Foundation

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 03, 2023

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Avenanthramides provide relief from a host of skin conditions, such as eczema, allergic rash, chicken pox and insect bites. Ceapro is the only commercial manufacturer of commercially available avenanthramides extracted and purified from oats.


Lead Product(s): Avenanthramide

Therapeutic Area: Immunology Product Name: Undisclosed

Highest Development Status: IND EnablingProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 22, 2022

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To advance this promising technology into clinical trials, the aim of the project is to optimize the delivery of PGX-YBG to lung and validate its performance for reducing lung fibrosis, both alone and loaded with an anti-inflammatory drug currently used for COVID-19 therapy.


Lead Product(s): PGX-YBG

Therapeutic Area: Infections and Infectious Diseases Product Name: PGX-YBG

Highest Development Status: PreclinicalProduct Type: Large molecule

Partner/Sponsor/Collaborator: McMaster University

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration August 11, 2022

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Under the agreement, Symrise is guaranteed to purchase minimum annual volumes of Ceapro’s high value active ingredients. These skills merge in the fields of active ingredients, biopharmaceuticals and drug-delivery solutions.


Lead Product(s): Oat Beta Glucan,Avenanthramides

Therapeutic Area: Dermatology Product Name: Juvente

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Symrise

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement March 10, 2022

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The effect of oat beta glucan on the study primary endpoint is change in LDL-C, and some positive findings observed with different parameters, there were dosage-related responses in weight and body-mass index at 12 weeks but they also did not reach statistical significance.


Lead Product(s): Beta Glucan

Therapeutic Area: Cardiology/Vascular Diseases Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 17, 2021

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Under the collaboration, pre-clinical studies using methods developed by the Angiogenesis Foundation will be conducted to characterize the in vivo bioactivity of Ceapro’s oat-derived bioactive products, beta glucan and avenanthramides.


Lead Product(s): Beta Glucan

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Angiogenesis Foundation

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration August 23, 2021

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