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    Bryn Pharma
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    Bryn Pharma’s UTULY™ 13.2mg Intranasal Epinephrine Spray Provides Higher and More Sustained PK Compared to Standard Reference Product, the 0.3mg Epi...

    Details:

    Utuly (epinephrine) is a nonselective alpha- and beta-adrenergic receptor agonist. Through its action on alpha-adrenergic receptors, it reduces vasodilation and increases vascular permeability that occurs during anaphylaxis.


    Lead Product(s): Epinephrine

    Therapeutic Area: Immunology Product Name: Utuly

    Highest Development Status: Phase IIIProduct Type: Small molecule

    Partner/Sponsor/Collaborator: Not Applicable

    Deal Size: Not Applicable Upfront Cash: Not Applicable

    Deal Type: Not Applicable February 24, 2023

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    Bryn Pharma Announces Completion of its Pivotal Study Comparing UTULY™ Epinephrine Intranasal Spray vs. 0.3 mg Epinephrine Autoinjector for the Treatm...

    Details:

    Utuly, an epinephrine nasal spray, for the treatment of anaphylaxis. It is designed to provide patients with a life-saving treatment that is needle free, fits in a pocket, is easy to use, and complies with practice parameters.


    Lead Product(s): Epinephrine

    Therapeutic Area: Immunology Product Name: Utuly

    Highest Development Status: Phase IIIProduct Type: Small molecule

    Partner/Sponsor/Collaborator: Not Applicable

    Deal Size: Not Applicable Upfront Cash: Not Applicable

    Deal Type: Not Applicable September 13, 2022

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    Bryn Pharma Raises $11 Million in Financing to Advance Bi-Dose Epinephrine Nasal Spray for Anaphylaxis

    Details:

    Proceeds from the financing will be used to fund the remaining development and regulatory approval activities, and pre-launch commercialization program for BRYN-NDS1C, Bryn's bi-dose epinephrine nasal spray.


    Lead Product(s): Epinephrine

    Therapeutic Area: Immunology Product Name: BRYN-NDS1C

    Highest Development Status: IND EnablingProduct Type: Small molecule

    Partner/Sponsor/Collaborator: Undisclosed

    Deal Size: $26.0 million Upfront Cash: Undisclosed

    Deal Type: Financing August 04, 2020

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    Bryn Pharma Publishes Positive Results from Its Intranasal Epinephrine Preclinical Study Program In Three Peer-Reviewed Scientific Journals

    Details:

    The preclinical results described in the publications were used to support the advancement of BRYN-NDS1C into the human clinical trial program currently underway.


    Lead Product(s): Epinephrine

    Therapeutic Area: Immunology Product Name: Undisclosed

    Highest Development Status: UndisclosedProduct Type: Small molecule

    Partner/Sponsor/Collaborator: Not Applicable

    Deal Size: Not Applicable Upfront Cash: Not Applicable

    Deal Type: Not Applicable June 10, 2020

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    Bryn Pharma Presents Data Demonstrating Comparable Pharmacokinetic and Pharmacodynamic Effects of Intranasal Epinephrine

    Details:

    Intranasal (IN) delivery of epinephrine from Bryn's needle-free Bi-dose Epinephrine Nasal Spray was comparable to intramuscular (IM) injection in pharmacokinetics, pharmacodynamics, and safety.


    Lead Product(s): Epinephrine

    Therapeutic Area: Immunology Product Name: Undisclosed

    Highest Development Status: Phase IProduct Type: Small molecule

    Partner/Sponsor/Collaborator: Not Applicable

    Deal Size: Not Applicable Upfront Cash: Not Applicable

    Deal Type: Not Applicable April 06, 2020

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