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BL-001 is a first-in-class, orally delivered, live biotherapeutic product being developed by Bloom Science for the treatment of multiple neurological diseases, including Dravet syndrome and ALS.


Lead Product(s): BL-001

Therapeutic Area: Neurology Product Name: BL-001

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 17, 2023

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BL-001 is a live biotherapeutic product, designed to modulate GABA and other key bioenergetic pathways to suppress hyperexcitability which is a key driver in seizures associated with dravet syndrome and other rare developmental and epileptic encephalopathies (DEEs).


Lead Product(s): BL-001

Therapeutic Area: Neurology Product Name: BL-001

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 25, 2023

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The investment will enable Bloom to file an Investigational New Drug (IND) application for BL-001 in refractory epilepsy and advance into Phase I clinical trials, as well as further expand development of its platform and advance its research and talent acquisition.


Lead Product(s): BL-001

Therapeutic Area: Neurology Product Name: BL-001

Highest Development Status: PreclinicalProduct Type: Large molecule

Partner/Sponsor/Collaborator: Leaps by Bayer

Deal Size: $12.0 million Upfront Cash: Undisclosed

Deal Type: Series A Financing December 09, 2021

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Bloom is leveraging its GOLD platform in combination with strong pre-clinical data to advance a new generation of therapeutics aimed at managing gut microbiota.


Lead Product(s): BL-001

Therapeutic Area: Neurology Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Undisclosed

Partner/Sponsor/Collaborator: ALS Association

Deal Size: $0.5 million Upfront Cash: Undisclosed

Deal Type: Funding March 17, 2020

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