Polpharma European CDMO Partner & API Manufacturer since 1951 Polpharma European CDMO Partner & API Manufacturer since 1951

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BRB-002 is a novel protein therapy targeting CD47 that is being investigated as a potential treatment option for patients with atherosclerotic cardiovascular disease (ASCVD).


Lead Product(s): BRB-002

Therapeutic Area: Cardiology/Vascular Diseases Product Name: BRB-002

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 29, 2024

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This collaboration will focus on discovering and developing medicines that may offer new hope for patients suffering from atherosclerosis and other life-threatening cardiovascular conditions.


Lead Product(s): Undisclosed

Therapeutic Area: Cardiology/Vascular Diseases Product Name: Undisclosed

Highest Development Status: DiscoveryProduct Type: Large molecule

Partner/Sponsor/Collaborator: Biotheus

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration February 26, 2024

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The net proceeds will be used to develop transformative medicines in cardio-immunology, including company’s lead program targeting the CD47/SIRPα pathway, designed to address the underlying dysfunction that contributes to atherosclerosis.


Lead Product(s): Undisclosed

Therapeutic Area: Cardiology/Vascular Diseases Product Name: Undisclosed

Highest Development Status: UndisclosedProduct Type: Large molecule

Partner/Sponsor/Collaborator: ARCH Venture Partners

Deal Size: $145.0 million Upfront Cash: Undisclosed

Deal Type: Series A Financing June 07, 2023

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