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ProLectin-M (galactomannan) is a precise chemistry based molecule that binds to galectin like receptors on the N terminal of S1 subunit of the Sars-CoV2 virus. It is being evaluated for the treatment of COVID-19.


Lead Product(s): Galactomannan

Therapeutic Area: Infections and Infectious Diseases Product Name: Prolectin-M

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 21, 2024

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ProLectin-M (galactomannan) is a chewable polysaccharide tablet for the treatment of mild to moderate and early stage COVID-19 Patients. The trial’s objective is to provide guidance for a 408 patient Phase III trial.


Lead Product(s): Galactomannan

Therapeutic Area: Infections and Infectious Diseases Product Name: ProLectin-M

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 24, 2023

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ProLectin-M (galactomannan) is a chewable polysaccharide tablet for the treatment of mild to moderate and early stage COVID-19 Patients. The trial’s objective is to provide guidance for a 408 patient Phase III trial.


Lead Product(s): Galactomannan

Therapeutic Area: Infections and Infectious Diseases Product Name: ProLectin-M

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Alke Research Private Limited

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 08, 2023

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The proceeds will help to start the dosage optimization study for mild to moderate COVID-19, which has already received the regulatory approval to proceed with dosing of ProLectin-M, an oral galectin antagonist that prevents the entry of the SARS-CoV-2 virus into human cells.


Lead Product(s): Galactomannan

Therapeutic Area: Infections and Infectious Diseases Product Name: ProLectin M

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Triton Funds

Deal Size: $0.5 million Upfront Cash: Undisclosed

Deal Type: Financing June 12, 2023

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BXT-25 is a intravenous version of hyperbaric oxygen treatment that lasts 9-18 hours and without any harmful side effects. It is a new paradigm in the way strokes and neurodegenerative diseases such as alzheimer’s, dementia, and traumatic brain injury are treated.


Lead Product(s): BXT-25

Therapeutic Area: Neurology Product Name: BXT-25

Highest Development Status: PreclinicalProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 19, 2023

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ProLectin-I binds to the ‘galectin fold’ of the spike protein thereby neutralizing a replication and ability of virus to infect other cells, it also binds to spike protein fragments thought to be the cause of ongoing inflammation. It is expected to treat Long COVID and IPF.


Lead Product(s): ProLectin-I

Therapeutic Area: Infections and Infectious Diseases Product Name: ProLectin-I

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 06, 2023

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ProLectin-M having galactomannan, is a new class of antiviral drug designed to antagonize galectins implicated in inflammatory, fibrotic, and malignant diseases.


Lead Product(s): Galactomannan

Therapeutic Area: Infections and Infectious Diseases Product Name: ProLectin-M

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 08, 2022

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The study shows direct binding of galectin-1 to the influenza virus, and intranasal treatment of galectin-1 could also enhance survival by reducing viral load, inflammation, and lung apoptosis.


Lead Product(s): BXT-10

Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Undisclosed

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 31, 2020

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Bioxytran seeks to explore collaborations with international drug makers to treat patients at the end stage of Acute Respiratory Distress Syndrome affected with Wuhan Coronavirus.


Lead Product(s): BXT-25

Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: Undisclosed

Highest Development Status: UndisclosedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Undisclosed

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Partnership February 05, 2020

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