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Biora Therapeutics
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BT-600 is a drug device combination containing liquid formulation of tofacitinib (JAK inhibitor). It is being evaluated for the treatment of ulcerative colitis


Lead Product(s): Tofacitinib Citrate

Therapeutic Area: Gastroenterology Product Name: BT-600

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 04, 2024

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Biora intends to use the net proceeds from this offering to support its operations, complete its ongoing BT-600 (tofacitinib) clinical trial for the treatment of moderate to severe ulcerative colitis.


Lead Product(s): Tofacitinib Citrate

Therapeutic Area: Gastroenterology Product Name: BT-600

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: H.C. Wainwright & Co

Deal Size: $6.0 million Upfront Cash: Undisclosed

Deal Type: Private Placement April 03, 2024

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Biora intends to use the proceeds to complete its ongoing clinical trial of BT-600, a drug-device combination consisting of the orally administered NaviCap device which delivers a unique, liquid formulation of tofacitinib to the colon for moderate to severe ulcerative colitis.


Lead Product(s): Tofacitinib Citrate

Therapeutic Area: Gastroenterology Product Name: BT-600

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: H.C. Wainwright & Co

Deal Size: $6.0 million Upfront Cash: Undisclosed

Deal Type: Public Offering April 01, 2024

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Details:

BT-600 (tofacitinib) is a drug-device combination program consisting of the orally administered NaviCap™ device which delivers a unique, liquid formulation of tofacitinib to the colon for the potential treatment of moderate to severe ulcerative colitis.


Lead Product(s): Tofacitinib Citrate

Therapeutic Area: Gastroenterology Product Name: BT-600

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 26, 2024

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Details:

BT-600 (tofacitinib) is a drug-device combination program consisting of the orally administered NaviCap™ device which delivers a unique, liquid formulation of tofacitinib to the colon for the potential treatment of moderate to severe ulcerative colitis.


Lead Product(s): Tofacitinib Citrate

Therapeutic Area: Gastroenterology Product Name: BT-600

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 08, 2024

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Details:

BT-600 (tofacitinib) is a drug/device combination designed to use Biora’s NaviCap™ ingestible drug delivery device with a proprietary liquid formulation of tofacitinib. It is being evaluated for the treatment of Ulcerative Colitis.


Lead Product(s): Tofacitinib Citrate

Therapeutic Area: Gastroenterology Product Name: BT-600

Highest Development Status: IND EnablingProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 29, 2023

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Details:

BT-600 program consists of a unique, liquid formulation of tofacitinib delivered to the colon via the NaviCap device, for the treatment of ulcerative colitis. Company has submitted an updated Investigational New Drug (IND) application for the same.


Lead Product(s): Tofacitinib Citrate

Therapeutic Area: Gastroenterology Product Name: BT-600

Highest Development Status: IND EnablingProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 30, 2023

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Details:

BT-600, a drug/device combination designed to use Biora’s NaviCap™ ingestible drug delivery device with a proprietary liquid formulation of tofacitinib, for the treatment of moderate to severe ulcerative colitis.


Lead Product(s): Tofacitinib Citrate

Therapeutic Area: Gastroenterology Product Name: BT-600

Highest Development Status: IND EnablingProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 23, 2023

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Details:

BT-600 (tofacitinib) is a drug/device combination delivering a liquid formulation of tofacitinib via the NaviCap™ platform for the treatment of ulcerative colitis.


Lead Product(s): Tofacitinib Citrate

Therapeutic Area: Gastroenterology Product Name: BT-600

Highest Development Status: IND EnablingProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 25, 2023

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Details:

The net proceeds will be used to invest in research and development of Biora's oral biotherapeutics platform, NaviCap™, a drug delivery system designed for delivery of BT-600, an orally delivered liquid formulation of tofacitinib for the treatment of ulcerative colitis.


Lead Product(s): Tofacitinib Citrate

Therapeutic Area: Gastroenterology Product Name: BT-600

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: H.C. Wainwright & Co.

Deal Size: $8.0 million Upfront Cash: Undisclosed

Deal Type: Public Offering June 14, 2023

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