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Arcutis Biotherapeutics
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2945 Townsgate Road, Suite 110 Westlake Village CA 91361
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805-418-5006
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The net proceeds will be used in the development and commercialization of Zoryve (roflumilast), which is a phosphodiesterase 4 inhibitor. It is being evaluated in clinical trial studies for the treatment of Atopic dermatitis.


Lead Product(s): Roflumilast

Therapeutic Area: Dermatology Product Name: Zoryve

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Morgan Stanley

Deal Size: $172.5 million Upfront Cash: Undisclosed

Deal Type: Public Offering March 04, 2024

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The net proceeds will be used in the development and commercialization of Zoryve (roflumilast), which is a phosphodiesterase 4 inhibitor. It is being evaluated in clinical trial studies for the treatment of Atopic dermatitis.


Lead Product(s): Roflumilast

Therapeutic Area: Dermatology Product Name: Zoryve

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Morgan Stanley

Deal Size: $150.0 million Upfront Cash: Undisclosed

Deal Type: Public Offering February 28, 2024

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The collaboration aims to enable Sato to concentrate on the development, manufacturing, and commercialization of topical Zoryve (roflumilast) in Japan. It is used in the treatment of Plaque Psoriasis.


Lead Product(s): Roflumilast

Therapeutic Area: Dermatology Product Name: Zoryve

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Sato Yakuhin Kogyo Co., Ltd

Deal Size: $40.0 million Upfront Cash: $25.0 million

Deal Type: Collaboration February 28, 2024

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Zoryve (roflumilast) is a highly potent and selective phosphodiesterase-4 (PDE4) inhibitor. Its topical foam (0.3%) is approved for treatment of seborrheic dermatitis in adult and pediatric patients 9 years of age and older.


Lead Product(s): Roflumilast

Therapeutic Area: Dermatology Product Name: Zoryve

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 22, 2024

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Zoryve (roflumilast) is a once-daily, PDE4 inhibitor steroid-free cream which is being investigated in phase 3 clinical trials for adults and children 6 years of age and older with atopic dermatitis.


Lead Product(s): Roflumilast

Therapeutic Area: Dermatology Product Name: Zoryve

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 14, 2024

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Details:

Zoryve (roflumilast) is a highly potent and selective phosphodiesterase-4 (PDE4) inhibitor. Its topical foam (0.3%) is approved for treatment of seborrheic dermatitis in adult and pediatric patients 9 years of age and older.


Lead Product(s): Roflumilast

Therapeutic Area: Dermatology Product Name: Zoryve

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 15, 2023

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Zoryve (roflumilast) topical foam, 0.3%, is indicated for treatment of seborrheic dermatitis in adult & pediatric patients 9 years of age & older. Zoryve, roflumilast cream 0.3%, is approved by FDA for the treatment of plaque psoriasis in individuals 6 years of age and older.


Lead Product(s): Roflumilast

Therapeutic Area: Dermatology Product Name: Zoryve

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 15, 2023

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Details:

Zoryve (roflumilast) is a PDE4 Inhibitor small molecule drug, formulated as a topical cream for the treatment of Atopic Dermatitis in Adults and Children Down to Age 6.


Lead Product(s): Roflumilast

Therapeutic Area: Dermatology Product Name: Zoryve

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 29, 2023

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Details:

Zoryve® (roflumilast cream) is a once-daily steroid free topical phosphodiesterase-4 (PDE4) inhibitor, which is used for topical treatment of Psoriasis in Children Ages 6 to 11.


Lead Product(s): Roflumilast

Therapeutic Area: Dermatology Product Name: Zoryve

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 20, 2023

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Details:

Arcutis intends to use the net proceeds to fund the continued development, approval and commercialization of its multiple programs, including for its potential launches in seborrheic dermatitis and atopic dermatitis and further patient expansion within psoriasis.


Lead Product(s): Roflumilast

Therapeutic Area: Dermatology Product Name: ARQ-154

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Morgan Stanley

Deal Size: $100.0 million Upfront Cash: Undisclosed

Deal Type: Public Offering October 19, 2023

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