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ANAVEX®3-71 (formerly AF710B) is a dual SIGMAR1 receptor agonist and M1 positive allosteric modulator with agonistic effect. It is being evaluated for the treatment of schizophrenia.


Lead Product(s): AF710B

Therapeutic Area: Psychiatry/Psychology Product Name: AF710B

Highest Development Status: Phase IIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 18, 2024

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ANAVEX®3-71 (formerly AF710B) is a dual SIGMAR1 receptor agonist and M1 positive allosteric modulator with agonistic effect. It is being evaluated in phase 1 clinical trials for the treatment of schizophrenia.


Lead Product(s): AF710B

Therapeutic Area: Neurology Product Name: ANAVEX 3-71

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 16, 2024

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ANAVEX 2-73 (blarcamesine) is an orally available drug candidate that restores cellular homeostasis by targeting sigma-1 and muscarinic receptors. It is under phase 3 clinical development for the treatment of patients with Rett syndrome (RTT).


Lead Product(s): Blarcamesine

Therapeutic Area: Genetic Disease Product Name: Anavex 2-73

Highest Development Status: Phase II/ Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 02, 2024

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ANAVEX 2-73 (blarcamesine) is an orally available drug candidate that restores cellular homeostasis by targeting sigma-1 and muscarinic receptors. It is under phase 3 clinical development for the treatment of patients with Rett syndrome (RTT).


Lead Product(s): Blarcamesine

Therapeutic Area: Genetic Disease Product Name: Anavex 2-73

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 20, 2023

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ANAVEX 2-73 (blarcamesine) is M1 & σ1 receptor agonist, which is being evaluated in phase 2/3 clinical trials for the treatment of Alzheimer’s Disease.


Lead Product(s): Blarcamesine

Therapeutic Area: Neurology Product Name: ANAVEX 2-73

Highest Development Status: Phase II/ Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 19, 2023

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Details:

ANAVEX2-73 (blarcamesine) is an orally available drug candidate that restores cellular homeostasis by targeting sigma-1 and muscarinic receptors. It is under phase 2/3 clinical development for the treatment of Alzheimer's disease.


Lead Product(s): Blarcamesine

Therapeutic Area: Neurology Product Name: ANAVEX2-73

Highest Development Status: Phase II/ Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 20, 2023

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ANAVEX®2-73 (blarcamesine) is an orally available drug candidate that restores cellular homeostasis by targeting sigma-1 and muscarinic receptors. It is being investigated for alzheimer’s disease.


Lead Product(s): Blarcamesine

Therapeutic Area: Neurology Product Name: Anavex 2-73

Highest Development Status: Phase II/ Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 14, 2023

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Details:

ANAVEX®2-73 (blarcamesine) is an orally available drug candidate that restores cellular homeostasis by targeting sigma-1 and muscarinic receptors. It is being investigated for rett syndrome.


Lead Product(s): Blarcamesine

Therapeutic Area: Genetic Disease Product Name: Anavex 2-73

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 28, 2023

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Details:

ANAVEX®2-73 (blarcamesine) is an orally available drug candidate that restores cellular homeostasis by targeting sigma-1 and muscarinic receptors. It is being investigated for rett syndrome.


Lead Product(s): Blarcamesine

Therapeutic Area: Genetic Disease Product Name: Anavex 2-73

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 15, 2023

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Details:

ANAVEX®2-73 (blarcamesine) is an orally available drug candidate that restores cellular homeostasis by targeting sigma-1 and muscarinic receptors. It is being investigated for rett syndrome.


Lead Product(s): Blarcamesine

Therapeutic Area: Genetic Disease Product Name: Anavex 2-73

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 06, 2023

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