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Anagram Therapeutics
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10 Speen Street | Framingham, MA 01701
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The collaboration aims to advance a pipeline of orally delivered enzymes targeting malabsorption syndromes and nutrient metabolism disorders, including ANG003, a novel broad-spectrum orally delivered enzyme replacement therapy.


Lead Product(s): ANG003

Therapeutic Area: Genetic Disease Product Name: ANG003

Highest Development Status: Phase IProduct Type: Large molecule

Recipient: Atum Bio

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Expanded Collaboration October 04, 2023

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If the therapy is successful, people with CF would be able to decrease the number of enzyme pills they must take to digest food properly from a handful of pills to only one per meal.


Lead Product(s): Enzyme-based Therapy

Therapeutic Area: Genetic Disease Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Large molecule

Partner/Sponsor/Collaborator: Cystic Fibrosis Foundation

Deal Size: $15.5 million Upfront Cash: Undisclosed

Deal Type: Funding April 04, 2023

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The new funding will be used to advance preclinical development and early stage clinical trials for Synspira’s non-porcine enzyme replacement therapy, SNSP003.


Lead Product(s): SNSP003

Therapeutic Area: Gastroenterology Product Name: SNSP003

Highest Development Status: PreclinicalProduct Type: Large molecule

Partner/Sponsor/Collaborator: CF Foundation

Deal Size: $22.5 Million Upfront Cash: $14.0 million

Deal Type: Funding October 20, 2020

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