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ALM-488 is a proprietary fluorescent peptide-dye conjugate in the visible spectrum and can be visualized with fluorescently enabled instrumentation including filter modified loupe systems, portable handheld systems, microscopes and laparoscopes.


Lead Product(s): ALM-488

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: ALM-488

Highest Development Status: Phase IIIProduct Type: Peptide

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 23, 2022

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ALM-488 is a fluorescently labelled nerve targeting drug, which acts as an adjunct for the visualization of nerves at risk for injury during head and neck surgery. The Fast Track designation is based on a Phase 1/2 trial in patients undergoing head and neck surgery.


Lead Product(s): ALM-488

Therapeutic Area: Oncology Product Name: ALM-488

Highest Development Status: Phase I/ Phase IIProduct Type: Peptide

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 12, 2021

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Alume is conducting a Phase 1/2 clinical trial of ALM-488 in patients undergoing Head and Neck surgery. The Phase II SBIR grant is a follow-on 2–year award that will support testing of Alume's fluorescent nerve targeting agent in an ongoing Phase 1/2 clinical trial.


Lead Product(s): ALM-488

Therapeutic Area: Oncology Product Name: ALM-488

Highest Development Status: Phase I/ Phase IIProduct Type: Peptide

Partner/Sponsor/Collaborator: National Institutes of Health

Deal Size: $2.5 million Upfront Cash: Undisclosed

Deal Type: Funding December 15, 2020

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