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Details:
AIV001 (axitinib) is a novel intradermally administered product designed for local, prolonged treatment effect for dermatological conditions. Now it has completed phase 1/2 clinical trials for the treatment of patients with nonmelanoma skin cancer.
Lead Product(s): Axitinib
Therapeutic Area: Oncology Product Name: AIV001
Highest Development Status: Phase I/ Phase IIProduct Type: Small molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable December 11, 2023
Details:
AIV007 is a novel formulation using our JEL™ Technology designed for prolonged drug release. AIV007 targets multiple pathways including VEGFR, PDGFR, and FGFR to address neovascularization and fibrosis.
Lead Product(s): Lenvatinib
Therapeutic Area: Ophthalmology Product Name: AIV007
Highest Development Status: Phase IProduct Type: Small molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable May 22, 2023
Details:
Second clinical trial assessing AIV001 to address unmet needs of skin diseases building on the exploratory efficacy of AIV001 in an earlier trial in wound healing from surgical incision. AIV001 to be tested in patients with superficial or nodular basal cell carcinoma.
Lead Product(s): AIV001
Therapeutic Area: Oncology Product Name: AIV001
Highest Development Status: Phase I/ Phase IIProduct Type: Small molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable October 02, 2020
Details:
AIV001 was shown to be safe and well tolerated after local intradermal treatment of incisional wounds. Reduction in fibrosis was observed from single AIV001 treatment post-wounding.
Lead Product(s): AIV001
Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: AIV001
Highest Development Status: Phase I/ Phase IIProduct Type: Small molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable June 25, 2020