Lubrizol Life Science Health

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SPRAY DRYING

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Our particle & nanoparticle engineering expertise includes, among others, micronized particulates (eg jet-milling), spray drying, emulsions, suspensions, liposomes, LyoCells®, solid lipid nanoparticles, polymer nanoparticles, PEGPLUS™, coacervates and polyelectrolyte complexes, and micro/nano

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Pharma Service: API & Drug Product Development

Category: API Development

Sub Category: Spray Drying

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EMULSIONS

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Our particle & nanoparticle engineering expertise includes, among others, micronized particulates (eg jet-milling), spray drying, emulsions, suspensions, liposomes, LyoCells®, solid lipid nanoparticles, polymer nanoparticles, PEGPLUS™, coacervates and polyelectrolyte complexes, and micro/nano

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Pharma Service: API & Drug Product Development

Category: Formulation Development

Sub Category: Emulsion

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NANOPARTICLES FORMULATION

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Our passion for complex drug product development means that we can handle just about project, including dosage forms like nanoparticles, resorbable microspheres, films/patches, and lipid-based systems.

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Pharma Service: API & Drug Product Development

Category: Formulation Development

Sub Category: Liposome / Microsphere / Nanoparticle

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LIPOSOMES

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Our particle & nanoparticle engineering expertise includes, among others, micronized particulates (eg jet-milling), spray drying, emulsions, suspensions, liposomes, LyoCells®, solid lipid nanoparticles, polymer nanoparticles, PEGPLUS™, coacervates etc

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Pharma Service: API & Drug Product Development

Category: Formulation Development

Sub Category: Liposome / Microsphere / Nanoparticle

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HOT MELT EXTRUSION

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Lubrizol Life Science Health uses this approach for both solid oral dosage forms and drug eluting devices. Combined with our DOSE™ system to quickly hone in on the right polymer choice, HME is an excellent path to increased bioavailability.

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Pharma Service: API & Drug Product Development

Category: Formulation Development

Sub Category: Overview

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HIGH PRESSURE HOMOGENIZATION

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At Lubrizol Life Science Health we use Microfluidics'® homogenizers to accomplish this. We have capabilities that span early development to sterile cGMPclinical supply.

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Pharma Service: API & Drug Product Development

Category: Formulation Development

Sub Category: Overview

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SPECIALIST DOSAGE FORMS - SUSPENSION

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Our particle & nanoparticle engineering scientific expertise includes micronized particulates (eg jet-milling), spray drying, emulsions, suspensions, powders, liposomes, oral solid lipid nanoparticles, polymer nanoparticles, coacervates, etc.

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Pharma Service: API & Drug Product Development

Category: Formulation Development

Sub Category: Suspension

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PREFORMULATION

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Starting with DOSE™, our own preformulation system and proceeding through formulation, production for pre-clinical toxicology, scale up and clinical trial material production,

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Pharma Service: API & Drug Product Development

Category: Preformulation & Material Science

Sub Category: Overview

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WET MILLING & JET MILLING

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Lubrizol Life Science Health is a leader in nanomilling (wet milling and jet milling), microfluidization and spray drying. Currently, it is the only for-hire organization that can perform nanomilling under aseptic conditions at a commercial scale.

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Pharma Service: API & Drug Product Development

Category: Preformulation & Material Science

Sub Category: Particle Size Reduction & Micronization

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PARTICLE SIZE REDUCTION

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Lubrizol Life Science Health has a complete set of in-house milling technologies including ball, high energy and jet milling (Netzsch® and Dyno®-Mill). It can mill highly potent compounds and can also mill aseptically.

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Pharma Service: API & Drug Product Development

Category: Preformulation & Material Science

Sub Category: Particle Size Reduction & Micronization

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SOLUBILIZATION

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Lubrizol has developed a proprietary approach to solubilization using a combination of computational tools and empirical data. DOSE has resulted in several clinical products already and is the basis for much of Lubrizol's work.

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Pharma Service: API & Drug Product Development

Category: Preformulation & Material Science

Sub Category: Solubility Assessment & Enhancement

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ODOR & TASTE MASKING BY ENCAPSULATION

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Employed to protect a given API, taste masking or to facilitate targeted drug delivery, encapsulation is a proven drug taste & odor masking strategy that Lubrizol has been practicing for over 20 years.

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Pharma Service: API & Drug Product Development

Category: Preformulation & Material Science

Sub Category: Taste Masking

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ANTIBODY-DRUG COMPLEXES

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Using Lubrizol's proprietary approach, a targeting ligand or therapeutic large molecule is attached to a nanoparticle that is loaded with an API(s).

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Pharma Service: Drug Product Manufacturing

Category: Biologic Drugs

Sub Category: Antibody Drug Conjugate

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DRUG & DEVICE COMBINATION PRODUCTS

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We are the world's leading drug/device combination product development CRO. Whether it's a new chemical entity, a line extension or generic, we are equipped to handle the complete design, formulation and production of our client's drug eluting devices.

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Pharma Service: Drug Product Manufacturing

Category: Medical Device

Sub Category: Overview

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POLYMER PROCESSING

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Our polymer processing capabilities include hot melt extrusion, co-extrusion, and injection molding. We have also established preferred relationships with the world’s leading polymer suppliers.

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Pharma Service: Packaging

Category: Materials

Sub Category: Polymer

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BET SURFACE AREA

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Lubrizol Life Science Health has various Analytics and Characterization Equipments for analytical services.

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Pharma Service: Analytical

Category: Analytical Testing Services

Sub Category: BET Surface Area

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LYOPHILIZATION

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We have a 120 ft2 lyophilizer that builds upon our existing R&D and clinical lyophilization capability (2 R&D and 2 small-scale clinical lyophilizers). Our commercial lyophilizer is supported with both Clean-In-Place and Steam-In-Place capabilities.

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Pharma Service: Drug Product Manufacturing

Category: Lyophilization

Sub Category: Overview

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SOLID SOLUTIONS

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Used to modify bioavailability, solid solutions are another go-to technology. We offer several systems for preparing solid solutions including Hot Melt Extrusion and spray drying.

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Pharma Service: API & Drug Product Development

Category: Preformulation & Material Science

Sub Category: Solid State Characterization

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