Looking for 162652-95-1 / Vinflunine API manufacturers, exporters & distributors?
Vinflunine manufacturers, exporters & distributors
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API | Excipient name
Vinflunine
Synonyms
162652-95-1, Javlor, 20',20'-difluoro-3',4'-dihydrovinorelbine, Chebi:90241, 4'-deoxy-20',20'-difluoro-c'-norvincaleukoblastine, 5bf646324k
Unique Ingredient Identifier (UNII)
5BF646324K
About Vinflunine
Vinflunine is a bi-fluorinated derivative of the semi-synthetic vinca alkaloid vinorelbine with antitubulin, antineoplastic, and antiangiogenic activities. Vinflunine inhibits tubulin assembly without any stablization of assembled microtubules at concentrations comparable to those of other vinca alkaloids such as vincristine, vinblastine and vinorelbine; this effect on microtubule dynamics results in cell cycle arrest in mitosis and apoptosis. Compared to other vinca alkaloids, this agent binds weakly to the vinca-binding site, indicating that vinflunine may exhibit reduced neurotoxicity.
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For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.