Roflumilast API Manufacturers | Suppliers | Drug Master Files (DMF) | CEP

PharmaCompass offers a list of Roflumilast API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Roflumilast manufacturer or Roflumilast supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Roflumilast manufacturer or Roflumilast supplier.

PharmaCompass also assists you with knowing the Roflumilast API Price utilized in the formulation of products. Roflumilast API Price is not always fixed or binding as the Roflumilast Price is obtained through a variety of data sources. The Roflumilast Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Roflumilast

Synonyms

162401-32-3, Daxas, 3-(cyclopropylmethoxy)-n-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide, Daliresp, By217, Byk20869

Cas Number

162401-32-3

Unique Ingredient Identifier (UNII)

0P6C6ZOP5U

About Roflumilast

Roflumilast is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential antineoplastic activities. Upon administration, roflumilast and its active metabolite roflumilast N-oxide selectively and competitively bind to and inhibit PDE4, which leads to an increase of both intracellular levels of cyclic-3',5'-adenosine monophosphate (cAMP) and cAMP-mediated signaling. cAMP prevents phosphorylation of spleen tyrosine kinase (SYK) and abrogates activation of the PI3K/AKT/mTOR signaling pathway, which may result in the induction of apoptosis. PDE4, a member of the PDE superfamily that hydrolyses cAMP and 3',5'-cyclic guanosine monophosphate (cGMP) to their inactive 5' monophosphates, is upregulated in a variety of cancers and may contribute to chemoresistance; it also plays a key role in inflammation, especially in inflammatory airway diseases.

Roflumilast Manufacturers

A Roflumilast manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Roflumilast, including repackagers and relabelers. The FDA regulates Roflumilast manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Roflumilast API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Roflumilast manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Roflumilast Suppliers

A Roflumilast supplier is an individual or a company that provides Roflumilast active pharmaceutical ingredient (API) or Roflumilast finished formulations upon request. The Roflumilast suppliers may include Roflumilast API manufacturers, exporters, distributors and traders.

click here to find a list of Roflumilast suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Roflumilast Manufacturers | Traders | Suppliers

We have 22 companies offering Roflumilast

Get in contact with the supplier of your choice:

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.

List of all Manufacturers, Suppliers & Exporters of Roflumilast API listed on PharmaCompass with details of regulatory filings

Roflumilast

Synopsis

Chemistry

APIs // Active Pharmaceutical Ingredients

24 Suppliers

12 USDMF

6 EU WC

5 KDMF

10 NDC API

17 Listed Suppliers

DEVELOPMENTS

63 Drug(s) in Development

PRICE INFORMATION

API Reference Price

API Exports

API Imports

FDF Exports

INTERMEDIATES

4 Suppliers

DOSSIERs // Finished Dosage Forms

44 Dossiers

22 FDA Orange Book

12 Europe

2 Canada

1 South Africa

7 Listed Dossiers

DRUG PRODUCT COMPOSITION

TABLET;ORAL - 250MCG

TABLET;ORAL - 500MCG

RELATED EXCIPIENT COMPANIES

Suppliers

15 Kerry

9 BASF

8 Microlex e.U

6 Roquette

5 Gangwal Healthcare

3 SPI Pharma

3 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

2 Sigachi Industries

2 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

2 DFE Pharma

2 Ingredion Pharma Solutions

1 Gangwal Chemicals

1 Vasa Pharmachem

1 Prachin Chemical

1 Nanjing Well Pharmaceutical

1 Boai NKY Pharmaceuticals Ltd

1 Ulanqab Kema New Material

1 Pharmatrans-Sanaq

1 Seppic

EXCIPIENTS BY APPLICATIONS

39 Fillers, Diluents & Binders

15 Direct Compression

10 Granulation

8 Lubricants & Glidants

7 Solubilizers

6 Co-Processed Excipients

6 Disintegrants & Superdisintegrants

5 Controlled & Modified Release

3 Parenteral

3 Chewable & Orodispersible Aids

3 Thickeners and Stabilizers

3 Taste Masking

2 Coating Systems & Additives

1 Film Formers & Plasticizers

1 Emulsifying Agents

GLOBAL SALES INFORMATION

8 US Medicaid Prescriptions

11 Finished Drug Prices

MARKET PLACE

13 APIs

1 DOSSIERS // FDF

PATENTS

21 US Patents

3 US Exclusivities

4 Health Canada Patents

ANALYTICAL SOLUTION(s)

5 Other Ref. Standards

DIGITAL CONTENT