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    Lusutrombopag

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    01 1Beijing Sjar Technology Development

    02 1Shionogi

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    Shionogi

    Japan

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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    Shionogi

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    NDC Package Code : 53044-003

    Start Marketing Date : 2018-08-26

    End Marketing Date : 2025-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

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    Beijing Sjar Technology Developmen...

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    Looking for 1110766-97-6 / Lusutrombopag API manufacturers, exporters & distributors?

    Lusutrombopag manufacturers, exporters & distributors 1

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    PharmaCompass offers a list of Lusutrombopag API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Lusutrombopag manufacturer or Lusutrombopag supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Lusutrombopag manufacturer or Lusutrombopag supplier.

    PharmaCompass also assists you with knowing the Lusutrombopag API Price utilized in the formulation of products. Lusutrombopag API Price is not always fixed or binding as the Lusutrombopag Price is obtained through a variety of data sources. The Lusutrombopag Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Lusutrombopag

    Synonyms

    1110766-97-6, Mulpleta, S-888711, 6ll5jfu42f, Rsc888711, (e)-3-[2,6-dichloro-4-[[4-[3-[(1s)-1-hexoxyethyl]-2-methoxyphenyl]-1,3-thiazol-2-yl]carbamoyl]phenyl]-2-methylprop-2-enoic acid

    Cas Number

    1110766-97-6

    Unique Ingredient Identifier (UNII)

    6LL5JFU42F

    About Lusutrombopag

    Lusutrombopag is an orally bioavailable thrombopoietin receptor (TPOR) agonist developed by Shionogi & Company (Osaka, Japan). TPOR is a regulatory target site for endogenous thrombopoietin, which acts as a primary cytokine to promote megakaryocyte proliferation and differentiation, and affect other hematopoietic lineages as well, including erythroid, granulocytic and lymphoid lineages. Thrombocytopenia, which indicates abnormally low levels of platelets, is a common complication related to chronic liver disease. This hematological abnormality, especially in cases of severe thrombocytopenia (platelet count <50,000/L), creates challenges to patients requiring invasive medical procedures where there is a significant risk for spontaneous bleeding. Lusutrombopag binds to the transmembrane domain of TPOR expressed on megakaryocytes, and causes the proliferation and differentiation of megakaryocytic progenitor cells from hematopoietic stem cells. In September 2015, lusutrombopag received its first global approval in Japan to reduce the need for platelet transfusion in adults with chronic liver disease and thrombocytopenia who are schedule to undergo an invasive medical procedure. Lusutrombopag was approved by the FDA on July 31st, 2018 for the same therapeutic indication under the market name Mulpleta. In two randomized, double-blind, placebo-controlled trials, patients with chronic liver disease and severe thrombocytopenia who were undergoing an invasive procedure with a platelet count less than 50 x 10^9/L were administered lusutrombopag orally. Higher percentages (65-78%) of the patients receiving lusutrombopag required no platelet transfusion prior to the primary invasive procedure compared to those receiving placebo. Lusutrombopag is currently in phase III development in various European countries including Austria, Belgium, Germany, and the UK.

    Lusutrombopag Manufacturers

    A Lusutrombopag manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Lusutrombopag, including repackagers and relabelers. The FDA regulates Lusutrombopag manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Lusutrombopag API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Lusutrombopag manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Lusutrombopag Suppliers

    A Lusutrombopag supplier is an individual or a company that provides Lusutrombopag active pharmaceutical ingredient (API) or Lusutrombopag finished formulations upon request. The Lusutrombopag suppliers may include Lusutrombopag API manufacturers, exporters, distributors and traders.

    click here to find a list of Lusutrombopag suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Lusutrombopag Manufacturers | Traders | Suppliers

    Lusutrombopag Manufacturers, Traders, Suppliers 1
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    We have 2 companies offering Lusutrombopag

    Get in contact with the supplier of your choice:

    1. Beijing Sjar Technology Development
    2. Shionogi
    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.